Partial D

DesignationISBT nameClusterHaplotypeMechanismAlterationsFirst mentionDefinitive publication
D-SPMRHD*40
RHD*D-SPM
DIVa clustercDeMultiple missense mutations186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
509T>C (M170T)
667T>G (F223V)
2012
DAR(CE2:V50V-S68N)RHD*09.06
RHD*DAR6
RHD*DAR(SE2:v50V-S68N)
weak D type 4 clustercDeComplex changes1025T>C (I342T)
150T>C
178A>C (I60L)
201G>A
203G>A (S68N)
602C>G (T201R)
667T>G (F223V)
957 G>A
2013
DAR(T203A)RHD*09.01
RHD*DAR
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
607A>G (T203A)
667T>G (F223V)
744C>T
957 G>A
20122012
DAR-ERHD*09.02
RHD*DAR2
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
697G>C (E233Q)
957 G>A
20062006
DAR1 (weak D type 4.2.0)RHD*09.01.00
RHD*DAR1.00
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
19981999
DAR2.1RHD*09.02.01
RHD*DAR2.01
weak D type 4 clusternot reportedMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
697G>C (E233Q)
744C>T
957 G>A
DAU-0RHD*10.00
RHD*DAU0
DAU clustercDeSingle missense mutation1136C>T (T379M)
20022002
DAU-1RHD*10.01
RHD*DAU1
DAU clustercDeMultiple missense mutations1136C>T (T379M)
689G>T (S230I)
20022002
DAU-2RHD*10.02
RHD*DAU2
DAU clustercDeMultiple missense mutations1136C>T (T379M)
209G>A (R70Q)
998G>A (S333N)
20022002
DAU-3RHD*10.03
RHD*DAU3
DAU clustercDeMultiple missense mutations1136C>T (T379M)
835G>A (V279M)
20022002
DAU-4RHD*10.04
RHD*DAU4
DAU clustercDeMultiple missense mutations1136C>T (T379M)
697G>A (E233K)
20022002
DAU-5RHD*10.05
RHD*DAU5
DAU clustercDeMultiple missense mutations1136C>T (T379M)
667T>G (F223V)
697G>C (E233Q)
20052005
DAU-6RHD*10.06
RHD*DAU6
DAU clustercDeMultiple missense mutations1136C>T (T379M)
998G>A (S333N)
20052005
DAU-7RHD*10.07
RHD*DAU7
DAU clustercDeSingle missense mutation1136C>T (T379M)
835G>A (V279M)
998G>A (S333N)
20092009
DBS-0RHD*05.03
RHD*DV.3
Eurasian D clusterCDehybrid alleleHybrid RHcE[226P](5:667-5:712)
19961996
DBS-1RHD*13.01
RHD*DBS1
Eurasian D clustercDEhybrid alleleHybrid RHcE[226P](5:667-5:800)
20012001
DBS-2RHD*13.02
RHD*DBS2
Eurasian D clustercDEhybrid alleleHybrid RHcE[226P](5:667-5:697)
20092012
DBT-1RHD*14.01
RHD*DBT1
Eurasian D clusterCDehybrid alleleHybrid RHCE(5-7)
19961996
DBT-2RHD*14.02
RHD*DBT2
Eurasian D clusterCDehybrid alleleHybrid RHCE(5-9)
19991999
DBURHD*41
RHD*DBU
RHD*01EL.23
Eurasian D clustercDEhybrid alleleHybrid RHcE[226P](5-7)
20082009
DCCRHD*42
RHD*DCC
Eurasian D clusterCDeSingle missense mutation677C>A (A226D)
20072012
DCS-1RHD*16.01
RHD*DCS1
Eurasian D clustercDEhybrid allele667T>G (F223V)
676G>C (A226P)
19992008
DCS-2RHD*16.02
RHD*DCS2
Eurasian D clustercDESingle missense mutation676G>C (A226P)
20082008
DDERHD*27
RHD*DDE
Eurasian D clusternot reportedSingle missense mutation120T>A (D40E)
2007
DDNRHD*43
RHD*DDN
Eurasian D clusternot reportedSingle missense mutation490G>A (D164N)
2008
DFLRHD*28
RHD*DFL
Eurasian D clusterCDeSingle missense mutation494A>G (Y165C)
20052007
DFR-1RHD*17.01
RHD*DFR1
Eurasian D clustermultiplehybrid alleleHybrid RHCE(4:505-4:514)
19951995
DFR-2RHD*17.02
RHD*DFR2
Eurasian D clusterCDehybrid alleleHybrid RHCE(4)
19971997
DFR-3RHD*17.03
RHD*DFR3
Eurasian D clusterCDeComplex changes539G>C (G180A)
Hybrid RHCE(4:505-4:514)
20072007
DFR-4RHD*17.04
RHD*DFR4
Eurasian D clusterCDehybrid alleleHybrid RHCE(4:505-4:509)
20092012
DFR-5RHD*17.05
RHD*DFR5
Eurasian D clusternot reportedhybrid alleleHybrid RHCE(3-4)
2007
DFVRHD*08.01
RHD*DFV
weak D type 4 clustermultipleSingle missense mutation667T>G (F223V)
20022002
DFWRHD*18
RHD*DFW
Eurasian D clusterCDeSingle missense mutation497A>C (H166P)
19982009
DHAREurasian D clustercdehybrid alleleHybrid RHCE(1-4)
Hybrid RHCE(6-10)
19961996
DHKRHD*05.05
RHD*DV.5
Eurasian D clusterCDeSingle missense mutation697G>A (E233K)
19981999
DHMiRHD*19
RHD*DHMi
Eurasian D clustercDESingle missense mutation848C>T (T283I)
1996
DHMiiEurasian D clustercDEhybrid allele1996
DHORHD*20
RHD*DHO
Eurasian D clusterCDeSingle missense mutation704A>C (K235T)
20012001
DHQRHD*44
RHD*DHQ
Eurasian D clusternot reportedSingle missense mutation513C>A (H171Q)
2004
DHRRHD*22
RHD*DHR
Eurasian D clusternot reportedSingle missense mutation686G>A (R229K)
19971997
DIIRHD*02
RHD*DII
Eurasian D clusterCDeSingle missense mutation1061C>A (A354D)
19971997
DIII type 4RHD*03.04
RHD*DIII.4
DIVa clusterCDehybrid allele186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
20002000
DIII type 5RHD*03.01
RHD*DIIIa
DIVa clustercDeMultiple missense mutations186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
DIII type 6RHD*03.06
RHD*DIII.6
DIVa clustercDeMultiple missense mutations410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
20052006
DIII type 7RHD*03.07
RHD*DIII.07
DIVa clustercDeComplex changes410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
Hybrid RHCE(2)
20052006
DIII type 8RHD*03.08
RHD*DIII.08
DIVa clusternot reportedMultiple missense mutations410C>T (A137V)
455A>C (N152T)
2010
DIIIcRHD*03.03
RHD*DIIIc
Eurasian D clusterCDehybrid alleleHybrid RHCE(3)
19961996
DIMRHD*34
RHD*DIM
Eurasian D clustercDESingle missense mutation854G>A (C285Y)
20002000
DIV type 1.0RHD*04.01
RHD*DIVa.
DIVa clustercDeMultiple missense mutations1048G>C (D350H)
186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
2012
DIV type 3RHD*04.03
RHD* DIV.3
Eurasian D clusterCDehybrid alleleHybrid RHCE(6-9)
19991999
DIV type 4RHD*04.04
RHD*DIV.4
Eurasian D clusterCDehybrid alleleHybrid RHCE(7:1048-7:1061)
1998
DIV type 5RHD*04.05
RHD*DIV.5
Eurasian D clustercDEhybrid alleleHybrid RHCE(7-9)
20002000
DIVb type 2RHD*04.06
RHD* DIVb
Eurasian D clusterCDehybrid alleleHybrid RHCE(7:1048-9)
19951995
DKKRHD*45
RHD*DKK
Eurasian D clustercDEhybrid alleleHybrid RHCE(2-3)
20002001
DLORHD*36
RHD*DLO
Eurasian D clusternot reportedSingle missense mutation851C>T (S284L)
20032004
DLXRHD*46
RHD*DLX
Eurasian D clustercDEComplex changes667T>G (F223V)
Hybrid RHCE(5:712-6)
20122012
DMHRHD*23
RHD*DMH
Eurasian D clusterCDeMissense (splice site affected)161T>C (L54P)
1999
DMIRHD*47
RHD*DMI
Eurasian D clusterCDeSingle missense mutation510G>A (M170I)
20082009
DMI-1.1RHD*47.01
RHD*DMI-1.1
Eurasian D clusterCDeSingle missense mutation510G>T (M170I)
2010
DNAKRHD*24
RHD*DNAK
Eurasian D clustercDESingle missense mutation1070G>A (G357D)
2005
DNBRHD*25
RHD*DNB
Eurasian D clusterCDeSingle missense mutation1063G>A (G355S)
20022002
DNSRHD*48
RHD*DNS
Eurasian D clusternot reportedSingle missense mutation485A>G (N162S)
2006
DNTEurasian D clusterCDeSingle missense mutation455A>C (N152T)
20092013
DNURHD*26
RHD*DNU
Eurasian D clustercDESingle missense mutation1057G>A (G353R)
19971997
DOL-1RHD*12.01
RHD*DOL1
weak D type 4 clustercDeMultiple missense mutations509T>C (M170T)
667T>G (F223V)
19992009
DOL-2RHD*12.02
RHD*DOL2
weak D type 4 clusternot reportedMultiple missense mutations1132C>G (L378V)
509T>C (M170T)
667T>G (F223V)
20052009
DOL-3RHD*12.03
RHD*DOL3
weak D type 4 clusternot reportedMultiple missense mutations410C>T (A137V)
509T>C (M170T)
667T>G (F223V)
2005
DTORHD*30
RHD*DTO
weak D type 4 clusternot reportedMultiple missense mutations667T>G (F223V)
674C>T (S225F)
20052005
DV type 1RHD*05.01
RHD*DV.1
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:697)
19951995
DV type 10RHD*05.10
RHD*DV.10
Eurasian D clusternot reportedhybrid alleleHybrid RHce(5-6)
DV type 2RHD*05.02
RHD*DV.2
Eurasian D clusterCDehybrid alleleHybrid RHCE(5)
19951995
DV type 4RHD*05.04
RHD*DV.4
Eurasian D clusterCDeSingle missense mutation697G>C (E233Q)
19981999
DV type 6RHD*05.06
RHD*DV.6
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:712)
19981999
DV type 7RHD*05.07
RHD*DV.7
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:787)
20012001
DV type 8RHD*05.08
RHD*DV.8
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:744)
19981999
DV type 9RHD*05.09
RHD*DV.9
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:697-5:712)
19992000
DVI type 1RHD*06.01
RHD*DVI.1
Eurasian D clustercDEhybrid alleleHybrid RHcE[226P](4-5)
19971997
DVI type 2RHD*06.02
RHD*DVI.2
Eurasian D clusterCDehybrid alleleHybrid RHCE(4-6)
19941994
DVI type 3RHD*06.03
RHD*DVI.3
Eurasian D clusterCDehybrid alleleHybrid RHCE(3-6)
19981998
DVI type 3.2RHD*06.03.02
RHD*DVI.03.02
Eurasian D clusternot reportedhybrid allele1195G>A (A399T)
Hybrid RHCE(3-6)
DVI type 4RHD*06.04
RHD*DVI.4
Eurasian D clusterCDehybrid alleleHybrid RHCE(3-5)
20002006
DVIIRHD*07.01
RHD*DVII.1
Eurasian D clusterCDeSingle missense mutation329T>C (L110P)
19951995
DVII type 2RHD*07.02
RHD*DVII.2
Eurasian D clusterCDeMultiple missense mutations307T>C (S103P)
329T>C (L110P)
20012001
DVL-1RHD*31
RHD*DVL1
Eurasian D clusternot reportedIn frame deletion684delGAG (229delR)
20042006
DVL-2RHD*32
RHD*DVL2
Eurasian D clusternot reportedIn frame deletion705delGAA (235delK)
20062006
DWIRHD*33
RHD*DWI
Eurasian D clusterCDeSingle missense mutation1073T>C (M358T)
20042004
DWNRHD*49
RHD*DWN
Eurasian D clustercDehybrid alleleHybrid RHCE(7:1053-7:1061)
20132013
DYURHD*29
RHD*DYU
Eurasian D clustercDeSingle missense mutation700A>T (R234W)
20032005
RHD(A354T)RHD*50Eurasian D clusterCDeSingle missense mutation1060G>A (A354T)
20142014
RHD(D164E)RHD*61Eurasian D clusternot reportedSingle missense mutation492C>A (D164E)
RHD(del44L)RHD*51Eurasian D clusternot reportedIn frame deletion130delCTC
2013
RHD(F223S)RHD*52Eurasian D clustercDeSingle missense mutation668T>C (F223S)
20152016
RHD(IVS2-2delA)RHD*53
RHD*01EL.22
Eurasian D clusternot reportedShort deletionIVS2-2delA
2013
RHD(IVS4-2A>C)RHD*54Eurasian D clustercDESplice site mutationIVS4-2A>C
20142014
RHD(L81P)RHD*55Eurasian D clusternot reportedSingle missense mutation242T>C (L81P)
2009
RHD(M295I)RHD*11
RHD*weak partial 11
Eurasian D clusterCDeSingle missense mutation885G>T (M295I)
20012001
RHD(S103P)RHD*39Eurasian D clustercDESingle missense mutation307T>C (S103P)
19961996
RHD-RHCE(7)-RHDRHD*58Eurasian D clustercDEhybrid alleleHybrid RHCE(7)
2012
weak D type 11RHD*11
RHD*weak partial 11
Eurasian D clustercDeSingle missense mutation885G>T (M295I)
19991999
weak D type 15RHD*15
RHD*weak partial 15
Eurasian D clustercDESingle missense mutation845G>A (G282D)
19991999
weak D type 21RHD*21
RHD*weak partial D 21
Eurasian D clusterCDeSingle missense mutation938C>T (P313L)
20012001
weak D type 4.0RHD*09.03.01
RHD*DAR3
weak D type 4 clustercDeMultiple missense mutations602C>G (T201R)
667T>G (F223V)
819G>A
19991999
weak D type 4.0.1RHD*09.03
RHD*DAR3
weak D type 4 clustercDeMultiple missense mutations602C>G (T201R)
667T>G (F223V)
weak D type 4.2.1 (DAR1.1)RHD*09.01.01
RHD*DAR1.01
RHD*weak 4.2
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
957 G>A
20002000
weak D type 4.2.2 (DAR1.2)RHD*09.01.02
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
744C>T
957 G>A
20002000
weak D type 4.2.3 (DAR1.3)RHD*09.01.03
RHD*DAR1.03
weak D type 4 clustercDeMultiple missense mutations1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
744C>T
2008
weak D type 4.3RHD*09. 05
RHD*weak 4.3
weak D type 4 clustercDeMultiple missense mutations602C>G (T201R)
667T>G (F223V)
819G>A
872C>G (P291R)
2004
weak D type 57RHD*57
RHD*weak partial 57
Eurasian D clusternot reportedSingle missense mutation640C>T (L214F)
20072007