DHO

Structure

RHD(K235T)

Key changes from standard allele

704A>C (K235T)

ISBT allele designation

RHD*20
RHD*DHO

Nucleotide changes relative to "standard RHD"

c.704 A>C

Amino acid changes relative to standard protein

Lys to Thr at codon 235

K235T

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D; weakened D expression

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2002 AJ276016 (submitted 2000-03-01, released 2002-12-07)

First full publication: 2001 Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.

Serology

Partial D with overall weak D expression, probably lacks epitopes epD4, epD11, epD31 (epD1-37 model) Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.

Observations

Northern Germany: Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.

Additional comments

Last update: 2015-01-29 (yyyy-MM-dd)