DCS-1

Structure

RHD(F223V,A226P)

Key changes from standard allele

667T>G (F223V)
676G>C (A226P)

ISBT allele designation

RHD*16.01
RHD*DCS1

Nucleotide changes relative to "standard RHD"

c.[667 T>G;676 G>C]

Amino acid changes relative to standard protein

F223V, A226P

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 1999 AJ131502 (submitted 1998-12-15)

First full publication: 2008 Flegel WA et. al. Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

Antigen Dw negative Flegel WA et. al. Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.

Observations

Austria (general): Polin H et. al. Transfusion. 2007 Aug;47(8):1350-5.

Additional comments

This allele was first mentioned in abstract form 1998

Last update: 2012-03-25 (yyyy-MM-dd)