c.[667 T>G;676 G>C;697 G>C]
F223V, A226P, E233Q
Eurasian D cluster
First submission to GenBank: 2009 EU335052 (submitted 2007-12-04, released 2009-01-01)
First full publication: 2012 Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.
Partial D reacting with P3*249 and P3*290. Serologic pattern differs from DCS-2 in 4 of 9 monoclonals tested. Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.
China (general): Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.
This allele is listed as DBS-2 and not DCS-3, because the additional E233Q substitution has major impact. As expected, the serology is quite different from DCS. However, the DBS alleles are characterized by a combination of A226P and E233Q. For unknown reasons, this allele is listed by the ISBT twice, both as DBS2 (RHD*13.02) and as DCS-3 (RHD*16.02??)
Last update: 2018-02-17 (yyyy-MM-dd)