DFR-4

Structure

RHD-RHCE(4:505-4:509)-RHD

Key changes from standard allele

Hybrid RHCE(4:505-4:509)

ISBT allele designation

RHD*17.04
RHD*DFR4

Nucleotide changes relative to "standard RHD"

c.[505 A>C;509 T>G]

Amino acid changes relative to standard protein

M169L, M170R

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2009 EU604753 (submitted 2008-03-28, released 2009-12-01)

First full publication: 2012 Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

Similar reactivity as DFR-1 Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.

Observations

China (general): Ye L et. al. Transfusion. 2012 Feb;52(2):241-6.

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)