DIM

Structure

RHD(C285Y)

Key changes from standard allele

854G>A (C285Y)

ISBT allele designation

RHD*34
RHD*DIM

Nucleotide changes relative to "standard RHD"

c.854 G>A

Amino acid changes relative to standard protein

Cys to Tyr at codon 285

C285Y

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 2000 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708. (submitted 1999-08-13)

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D; weakened D expression

Serology

Rhesus index 0 Partial D: lacks epitopes 1 to 4, 7, 11, 17, 18, 20/21, 22, 31 to 35; expresses epitopes 5, 6, 10(part.), 12, 13, 15/16, 23, 36, 37 (30 epitope model) Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Observations

South Africa (general): Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)