DHAR

Structure

RHCE-RHD(5)-RHCE

Key changes from standard allele

Hybrid RHCE(1-4)
Hybrid RHCE(6-10)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

150 T>C, 178 A>C, 201 G>A, 203 G>A, 307 T>C, 361 T>A, 380 T>C, 383 A>G, 455 A>C, 505 A>C, 509 T>G, 514 A>T, 544 T>A, 577 G>A, 594 A>T, 602 C>G, 916 G>A, 932 A>G, 941 G>T, 968 C>A, 974 G>T, 979 A>G, 985 GG>CA, 989 A>C, 992 A>T, 1025 T>C, 1048 G>C, 1053 C>T, 1057 GGA>TGG, 1060 GC>AA, 1170 T>C, 1193 A>T

Amino acid changes relative to standard protein

, I60L, S68N, S103P, L121M, V127A, D128G, N152T, M169L, M170R, I172F, S182T, E193K, K198N, T201R, V306I, Y311C, G314V, P323H, S325I, I327V, G329H, Y330S, N331I, I342T, D350H, G353W, A354N, E398V

Haplotype (typical)

cde

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1996 Beckers EA et. al. Br J Haematol. 1996 Mar;92(3):751-7.

ISBT group

Phenotype characterization and grouping

Partial D

Serology

No data

Observations

No data

Additional comments

This allele is an RHCE allele, it is listed among the RHD alleles as it may appear as partial D. It expresses FPTT and a partial e antigen.

Last update: 2012-03-25 (yyyy-MM-dd)