DBU

Structure

RHD-cE(5-7;226P)-D

Key changes from standard allele

Hybrid RHcE[226P](5-7)

ISBT allele designation

RHD*41
RHD*DBU
RHD*01EL.23
RHD*DEL23

Nucleotide changes relative to "standard RHD"

667 T>G, 676 G>C, 697 G>C, 712 G>A, 733 G>C, 744 C>T, 787 G>A, 800 A>T, 916 G>A, 932 A>G, 941 G>T, 968 C>A, 974 G>T, 979 A>G, 985 GG>CA, 989 A>C, 992 A>T, 1025 T>C, 1048 G>C, 1053 C>T, 1057 GGA>TGG, 1060 GC>AA

Amino acid changes relative to standard protein

F223V, A226P, E233Q, V238M, V245L, G263R, K267M, V306I, Y311C, G314V, P323H, S325I, I327V, G329H, Y330S, N331I, I342T, D350H, G353W, A354N

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2008 AM945964 (submitted 2008-03-10, released 2008-09-10)

First full publication: 2009 Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71. (submitted 2008-05-23)

ISBT group

partial RHD

Phenotype characterization and grouping

DEL; Partial D

Serology

No data

Observations

No data

Additional comments

This allele is listed by ISBT as partial D RHD*41 and as DEL RHD*01EL*23 / RHD*DEL23

Last update: 2017-02-18 (yyyy-MM-dd)