DAR-E

Structure

RHD(T201R,F223V,E233Q,I342T)[957G>A]

Key changes from standard allele

1025T>C (I342T)
602C>G (T201R)
667T>G (F223V)
697G>C (E233Q)
957 G>A

ISBT allele designation

RHD*09.02
RHD*DAR2

Nucleotide changes relative to "standard RHD"

c.[602 C>G;667 T>G;697 G>C;957 G>A;1025 T>C]

Amino acid changes relative to standard protein

T201R, F223V, E233Q, I342T

Haplotype (typical)

cDe

Allele cluster

weak D type 4 cluster

Descriptions

First full publication: 2006 Grootkerk-Tax MG et. al. Transfusion. 2006 Apr;46(4):606-15.

Other relevant descriptions:
Tax MGHM Rh variability in multi-ethnic perspective (thesis)

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D; weakened D expression

Serology

Partial D with epitope profile differing from DAR Grootkerk-Tax MG et. al. Transfusion. 2006 Apr;46(4):606-15.

Observations

Ethiopia (general): Grootkerk-Tax MG et. al. Transfusion. 2006 Apr;46(4):606-15.

Related Alleles

DAR2.1 [RHD(T201R,F223V,E233Q,I342T)[744C>T, 957G>A]]

Additional comments

Last update: 2017-01-29 (yyyy-MM-dd)