DNT

Structure

RHD(N152T)

Key changes from standard allele

455A>C (N152T)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.455 A>C

Amino acid changes relative to standard protein

Asn to Thr at codon 152

N152T

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 2009 von Zabern I et al. Transfusion 2009;49 Suppl 3:119A.

First submission to GenBank: 2012 HF549084 (submitted 2012-11-02, released 2012-12-04)

First full publication: 2013 von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111

Other relevant descriptions:
Fong C et al. Transfusion 2012;52

ISBT group

Phenotype characterization and grouping

Partial D

Serology

HF549084: Anti-D
1 proband with anti-D von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111

Observations

Germany (general): von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111

Related Alleles

Ccdes-1 [RHD(L62F,A137V,N152T)-RHCE(4-7)-RHD(G336C)]
D-SPM [RHD(L62F,A137V,N152T,M170T,F223V)]
DIII type 4 [RHD(L62F,A137V,N152T)]
DIII type 4.2 [RHD(L62F,S103P,A137V,N152T)]
DIII type 5 [RHD(L62F,A137V,N152T,T201R,F223V)]
DIII type 6 [RHD(A137V,N152T,T201R,F223V,A273A)]
DIII type 7 [RHD-RHCE(2)-RHD(A137V,N152T,T201R,F223V)]
DIII type 8 [RHD(A137V,N152T)]
DIII type 9 [RHD(L62F,A137V,N152T,F223V)]
DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D [DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D]
DIIIa150C [RHD(150T>C,L62F,A137V,N152T,T201R,F223V,819G>A)]
DIV(S103P) [RHD(L62F,S103P,A137V,N152T)]
DIV-DOL [RHD(L62F,A137V,N152T,M170T,F223V)]
DIV type 1.1 [RHD(L62F,N152T,D350H)]
DIV type 1.0 [RHD(L62F,A137V,N152T,D350H)]
DOL-4 []
RHD(A137V,N152T)-CE(4-6)-D(7-10) [RHD(A137V,N152T)-CE(4-6)-D(7-10)]
RHD(I60L,N152T,T201R,F223V,G263R) [RHD(I60L,N152T,T201R,F223V,G263R)]
DIVa-like [RHD(L62F,A137V,N152T,F223V,D350H)]
RHD(N152T,T201R,F223V) [RHD(N152T,T201R,F223V)]
RHD(N152T,V270G) [RHD(N152T,V270G)]
DFR-5 [RHD-RHCE(3-4)-RHD]
DHAR [RHCE-RHD(5)-RHCE]
DVI type 4 [RHD-RHCE(3-5)-RHD]
DIIIc [RHD-RHCE(3)-RHD]
RHD-RHCE(3)--weak D type 4.0 [RHD-RHCE(3)-RHD(T201R,F223V,819G>A)]
DKK [RHD-RHCE(2-3)-RHD]
DVI type 3 [RHD-RHCE(3-6)-RHD]
DVI type 3.2 [RHD-RHCE(3-6)-RHD(A399T)]
RHCE(1-3)-RHD(4-10) [RHD(Hybrid RHCE(1-3))]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD-RHCe(2-7)-RHD [RHD-RHCE(3-7)-RHD]
RHD(L110P)-CE(3-9)-D [RHD(L110P)-CE(3-9)-D]
RHD(S68T)-RHCe(3-9)-RHD [RHD(S68T)-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD [RHD-RHCe(2-9)-RHD]
RHD-RHCe(2-9)-RHD1 [RHD-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD2 [RHD-RHCE(3-9)-RHD]
RHD-RHCE(2-5)-RHD [RHD-RHCE(2-5)-RHD]

Additional comments

Last update: 2016-08-28 (yyyy-MM-dd)