Ala to Asp at codon 354
Partial D; D category
Eurasian D cluster
First full publication: 1997 Avent ND et. al. Br J Haematol. 1997 May;97(2):366-71.
Partial D, lacks epitopes epD4 and epD9 Lomas C et. al. Transfus Med. 1993 Mar;3(1):67-9.
The molecular structure was established for an original â??D category IIâ?? sample. Therefore, the older serologic studies are representative for DII. The nucleotide substitution is templated, but the resulting amino acid is neither present in RhD nor RhCE since the respective codons of RHCE and RHD differ in more than one nucleotide. Anti-D immunizations have been reported.
Last update: 2012-03-27 (yyyy-MM-dd)