weak D type 21

Structure

RHD(P313L)

Key changes from standard allele

938C>T (P313L)

ISBT allele designation

RHD*21
RHD*weak partial D 21

Nucleotide changes relative to "standard RHD"

938 C>T

Amino acid changes relative to standard protein

Pro to Leu at codon 313

P313L

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2006 AJ276015 (submitted 2000-03-01, released 2006-11-14)

First full publication: 2001 Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.

ISBT group

partial RHD

Phenotype characterization and grouping

weak D type; Partial D; weakened D expression

Serology

weak D phenotype Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.
McGann H & Wenk RE Immunohematology. 2010;26(1):27-9.: Anti-D (2+)

Observations

Linz region: Polin H et. al. Transfusion. 2007 Aug;47(8):1350-5.
Northern Germany: Muller TH et. al. Transfusion. 2001 Jan;41(1):45-52.

Additional comments

Last update: 2017-02-19 (yyyy-MM-dd)