DHMi

Structure

RHD(T283I)

Key changes from standard allele

848C>T (T283I)

ISBT allele designation

RHD*19
RHD*DHMi

Nucleotide changes relative to "standard RHD"

c.848 C>T

Amino acid changes relative to standard protein

Thr to Ile at codon 283

T283I

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 1996 Liu, W., Jones, J.W., Scott, M.L., Voak, D., and Avent, N.D. Molecular analysis of two D-variants, DHMi and DHMii. Transfus.Med. 6(suppl 2):21, 1996. (Abstract)

Other relevant descriptions:
Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

Partial D Jones J Vox Sang. 1995;69(3):236-41.

Observations

Linz region: Polin H et. al. Transfusion. 2007 Aug;47(8):1350-5.
South-Western Germany: Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.
UK (general): Jones J Vox Sang. 1995;69(3):236-41.

Additional comments

Last update: 2012-03-27 (yyyy-MM-dd)