DCS-2

Structure

RHD(A226P)

Key changes from standard allele

676G>C (A226P)

ISBT allele designation

RHD*16.02
RHD*DCS2

Nucleotide changes relative to "standard RHD"

c.676 G>C

Amino acid changes relative to standard protein

Ala to Pro at codon 226

A226P

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2008 AM694189 (submitted 2007-04-16, released 2008-03-18)

First full publication: 2008 Flegel WA et. al. Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

Antigen Dw negative Flegel WA et. al. Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.

Observations

China (general): EU335050
Germany (general): Flegel WA et. al. Transfusion. 2008 Jan;48(1):25-33. Epub 2007 Sep 27.

Related Alleles

DCS-1 [RHD(F223V,A226P)]
DVI type 1 [RHD-RHcE(4-5)-RHD]
DBS-0 [RHD-RHcE(5:667-5:712)-RHD]
DBS-1 [RHD-RHcE(5:667-5:800)-RHD]
DBS-2 [RHD-RHcE(5:667-5:697)-RHD]
DBU [RHD-cE(5-7;226P)-D]
RHD-cE(5-6)-D [RHD-cE(5-6)-D]
RHD-RHcE[226P](5:676-5:733)-RHD [RHD-RHcE[226P](5:676-5:733)-RHD]

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)