DWN

Structure

RHD-RHCE(7:1053-7:1061)-RHD

Key changes from standard allele

Hybrid RHCE(7:1053-7:1061)

ISBT allele designation

RHD*49
RHD*DWN

Nucleotide changes relative to "standard RHD"

c.[1053 C>T;1057 GGA>TGG;1060 GC>AA]

Amino acid changes relative to standard protein

, G353W, A354N

Haplotype (typical)

cDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2013 HF549083 (submitted 2012-10-29, released 2013-01-07)

First full publication: 2013 von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

HF549083: anti-D
cDe haplotype; 1 proband with anti-D von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111

Observations

African ancestry (general): von Zabern I et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2960-73. doi: 10.1111
USA (general): HF549083

Related Alleles

Ccdes-1 [RHD(L62F,A137V,N152T)-RHCE(4-7)-RHD(G336C)]
Ccdes-2 [RHD-RHCE(4-7)-RHD(G336C)]
DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D [DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D]
DBT-1 [RHD-RHCe(5-7)-RHD]
DBT-2 [RHD-RHCe(5-9)-RHD]
DBU [RHD-cE(5-7;226P)-D]
DHAR [RHCE-RHD(5)-RHCE]
DIV type 3 [RHD-RHCE(6-9)-RHD]
DIV type 4 [RHD-RHCE(7:1048-7:1061)-RHD]
DIV type 5 [RHD-RHCE(7-9)-RHD]
DIVb (J) [RHD-RHCE(7-9)-RHD]
DIVb type 2 [RHD-RHCE(7:1048-9)-RHD]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD-RHCe(2-7)-RHD [RHD-RHCE(3-7)-RHD]
RHD(L110P)-CE(3-9)-D [RHD(L110P)-CE(3-9)-D]
RHD(S68T)-RHCe(3-9)-RHD [RHD(S68T)-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD [RHD-RHCe(2-9)-RHD]
RHD-RHCe(2-9)-RHD1 [RHD-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD2 [RHD-RHCE(3-9)-RHD]
RHD-RHCE(4-7)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD1 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD2 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-8)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-9)-RHD [RHD-RHCE(4-9)-RHD]
RHD(L214F)-CE(7)-D [RHD(L214F)-CE(7)-D]
RHD-RHCE(7)-RHD [RHD-RHCE(7)-RHD]
RHD(G353W,A354N) [RHD-RHCE(7:1053-7:1061)-RHD]

Additional comments

Last update: 2017-01-29 (yyyy-MM-dd)