DIVb type 2

Structure

RHD-RHCE(7:1048-9)-RHD

Key changes from standard allele

Hybrid RHCE(7:1048-9)

ISBT allele designation

RHD*04.06
RHD* DIVb

Nucleotide changes relative to "standard RHD"

c.[1048 G>C;1053 C>T;1057 GGA>TGG;1060 GC>AA;1170 T>C;1193 A>T]

Amino acid changes relative to standard protein

D350H, G353W, A354N, E398V

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1995 Rouillac C et. al. Blood. 1995 May 15;85(10):2937-44.

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

No data

Observations

No data

Related Alleles

DBT-2 [RHD-RHCe(5-9)-RHD]
DHAR [RHCE-RHD(5)-RHCE]
DIV type 3 [RHD-RHCE(6-9)-RHD]
DIV type 5 [RHD-RHCE(7-9)-RHD]
DIVb (J) [RHD-RHCE(7-9)-RHD]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD(L110P)-CE(3-9)-D [RHD(L110P)-CE(3-9)-D]
RHD(S68T)-RHCe(3-9)-RHD [RHD(S68T)-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD [RHD-RHCe(2-9)-RHD]
RHD-RHCe(2-9)-RHD1 [RHD-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD2 [RHD-RHCE(3-9)-RHD]
RHD-RHCE(4-9)-RHD [RHD-RHCE(4-9)-RHD]

Additional comments

In the original counting, DIVb was considered the second DIV-like allele (after DIVa, before the description of DIV type 3)

Last update: 2016-08-28 (yyyy-MM-dd)