D-SPM

Structure

RHD(L62F,A137V,N152T,M170T,F223V)

Key changes from standard allele

186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
509T>C (M170T)
667T>G (F223V)

ISBT allele designation

RHD*40
RHD*D-SPM

Nucleotide changes relative to "standard RHD"

186 G>T, 410 C>T, 455 A>C, 509 T>C, 667 T>G

Amino acid changes relative to standard protein

L62F, A137V, N152T, M170T, F223V

Haplotype (typical)

cDe

Usually linked to ceBI

Allele cluster

DIVa cluster

Descriptions

First submission to GenBank: 2012 JX193763 (submitted 2012-06-17, released 2012-08-29)

Other relevant descriptions:
DIV-DOL HG423859 (submitted 2013-07-18, released 2013-09-18)

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

No data

Observations

African ancestry (general): HG423859

Additional comments

Partial D status putative. This allele was first described as D-SPM and later independently as DIV-DOL

Last update: 2017-01-29 (yyyy-MM-dd)