weak D type 124

Structure

RHD(K198N)

Key changes from standard allele

594A>T (K198N)

ISBT allele designation

RHD* 01W.124
RHD*weak D type 124

Nucleotide changes relative to "standard RHD"

c.594 A>T

Amino acid changes relative to standard protein

Lys to Asn at codon 198

K198N

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2015 LC075274 (submitted 2015-08-17, released 2015-09-08)

ISBT group

weak D

Phenotype characterization and grouping

weakened D expression; weak D type

Serology

weak D LC075274

Observations

Japan (general): LC075274

Related Alleles

Ccdes-1 [RHD(L62F,A137V,N152T)-RHCE(4-7)-RHD(G336C)]
Ccdes-2 [RHD-RHCE(4-7)-RHD(G336C)]
DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D [DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D]
DVI type 2 [RHD-RHCE(4-6)-RHD]
RHD(A137V,N152T)-CE(4-6)-D(7-10) [RHD(A137V,N152T)-CE(4-6)-D(7-10)]
DVI type 1 [RHD-RHcE(4-5)-RHD]
DFR-2 [RHD-RHCE(4)-RHD]
DFR-5 [RHD-RHCE(3-4)-RHD]
DHAR [RHCE-RHD(5)-RHCE]
DVI type 4 [RHD-RHCE(3-5)-RHD]
DVI type 3 [RHD-RHCE(3-6)-RHD]
DVI type 3.2 [RHD-RHCE(3-6)-RHD(A399T)]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD-RHCe(2-7)-RHD [RHD-RHCE(3-7)-RHD]
RHD(L110P)-CE(3-9)-D [RHD(L110P)-CE(3-9)-D]
RHD(S68T)-RHCe(3-9)-RHD [RHD(S68T)-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD [RHD-RHCe(2-9)-RHD]
RHD-RHCe(2-9)-RHD1 [RHD-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD2 [RHD-RHCE(3-9)-RHD]
RHD-RHCE(4-7)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD1 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD2 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-8)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-9)-RHD [RHD-RHCE(4-9)-RHD]
weak D type 4.4 [RHD(K198N,T201R,F223V)]
weak D type 14 [RHD(S182T,K198N,T201R)]
weak D type 29 [RHD(I60L,S68N,K198N,F223V,I342T)]
RHD(I60L,S68N,K198N,F223V,G314V,I342T) [RHD(I60L,S68N,K198N,F223V,G314V,I342T)]
weak D type 51 [RHD-RHCE(4:594-4:602)-RHD]
RHD-RHCE(2-5)-RHD [RHD-RHCE(2-5)-RHD]

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)