RHD(L110P)-CE(3-9)-D

Structure

RHD(L110P)-CE(3-9)-D

Key changes from standard allele

329T>C (L110P)
Hybrid RHCE(3-9)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.[329 T>C;361 T>A;380 T>C;383 A>G;455 A>C;505 A>C;509 T>G;514 A>T;544 T>A;577 G>A;594 A>T;602 C>G;667 T>G;697 G>C;712 G>A;733 G>C;744 C>T;787 G>A;800 A>T;916 G>A;932 A>G;941 G>T;968 C>A;974 G>T;979 A>G;985 GG>CA;989 A>C;992 A>T;1025 T>C;1048 G>C;1053 C>T;1057 GGA>TGG;1060 GC>AA;1170 T>C;1193 A>T]

Amino acid changes relative to standard protein

L110P, L121M, V127A, D128G, N152T, M169L, M170R, I172F, S182T, E193K, K198N, T201R, F223V, E233Q, V238M, V245L, G263R, K267M, V306I, Y311C, G314V, P323H, S325I, I327V, G329H, Y330S, N331I, I342T, D350H, G353W, A354N, E398V

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 2014 Trucco Boggione C et. al. Transfusion. 2014 Oct;54(10):2456-62. doi: 10.1111/trf.12691. Epub 2014 May 12.

ISBT group

Phenotype characterization and grouping

Serology

D negative Trucco Boggione C et. al. Transfusion. 2014 Oct;54(10):2456-62. doi: 10.1111/trf.12691. Epub 2014 May 12.

Observations

Brazil (general): Trucco Boggione C et. al. Transfusion. 2014 Oct;54(10):2456-62. doi: 10.1111/trf.12691. Epub 2014 May 12.

Additional comments

Last update: 2018-01-29 (yyyy-MM-dd)