DUC-2

Structure

RHD(V245L)

Key changes from standard allele

733G>C (V245L)

ISBT allele designation

RHD*37
RHD*DUC2

Nucleotide changes relative to "standard RHD"

c.733 G>C

Amino acid changes relative to standard protein

Val to Leu at codon 245

V245L

ISBT group

partial RHD

Phenotype characterization and grouping

D positive (apparently normal)

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2005 AY864888 (submitted 2004-12-23, released 2005-08-09)

First full publication: 2005 Chen Q & Flegel WA Transfusion. 2005 Jul;45(7):1183-91.

Serology

Apparently normal D Chen Q & Flegel WA Transfusion. 2005 Jul;45(7):1183-91.

Observations

South-Western Germany: Chen Q & Flegel WA Transfusion. 2005 Jul;45(7):1183-91.

Related Alleles

DVI type 2 [RHD-RHCE(4-6)-RHD]
RHD(A137V,N152T)-CE(4-6)-D(7-10) [RHD(A137V,N152T)-CE(4-6)-D(7-10)]
DVI type 1 [RHD-RHcE(4-5)-RHD]
DBS-1 [RHD-RHcE(5:667-5:800)-RHD]
DBT-1 [RHD-RHCe(5-7)-RHD]
DBT-2 [RHD-RHCe(5-9)-RHD]
DBU [RHD-cE(5-7;226P)-D]
DVI type 4 [RHD-RHCE(3-5)-RHD]
RHD(V245L,G263R,K267M) [RHD(V245L,G263R,K267M)]
DV type 2 [RHD-RHCE(5)-RHD]
RHD(T201R)-CE(5)-D(I342T) [RHD(T201R)-CE(5)-D(I342T)]
DV type 8 [RHD-RHCE(5:667-5:744)-RHD]
DV type 7 [RHD-RHCE(5:667-5:787)-RHD]
DVI type 3 [RHD-RHCE(3-6)-RHD]
DVI type 3.2 [RHD-RHCE(3-6)-RHD(A399T)]
DV type 10 [RHD-RHCE(5-6)-RHD]
DLX [RHD(F223V)-RHCE(5:712-6)-RHD]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD-RHCe(2-7)-RHD [RHD-RHCE(3-7)-RHD]
RHD(L110P)-CE(3-9)-D [RHD(L110P)-CE(3-9)-D]
RHD(S68T)-RHCe(3-9)-RHD [RHD(S68T)-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD [RHD-RHCe(2-9)-RHD]
RHD-RHCe(2-9)-RHD1 [RHD-RHCE(3-9)-RHD]
RHD-RHCe(2-9)-RHD2 [RHD-RHCE(3-9)-RHD]
RHD-RHCE(4-7)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD1 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-7)-RHD2 [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-8)-RHD [RHD-RHCE(4-7)-RHD]
RHD-RHCE(4-9)-RHD [RHD-RHCE(4-9)-RHD]
RHD-cE(5-6)-D [RHD-cE(5-6)-D]
RHD-RHcE[226P](5:676-5:733)-RHD [RHD-RHcE[226P](5:676-5:733)-RHD]
RHD-RHCE(5:733-5:787)-RHD [RHD-RHCE(5:733-5:787)-RHD]
RHD-RHCE(2-5)-RHD [RHD-RHCE(2-5)-RHD]
RHCE(5:697-5:744)-RHD [RHD-RHCE(5:697-5:744)-RHD]

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)