RHCE(1-3)-RHD(4-10)

Structure

RHD(Hybrid RHCE(1-3))

Key changes from standard allele

Hybrid RHCE(1-3)

ISBT allele designation

RHD*01N.43

Nucleotide changes relative to "standard RHD"

c.[150 T>C;178 A>C;201 G>A;203 G>A;307 T>C;361 T>A;380 T>C;383 A>G;455 A>C]

Amino acid changes relative to standard protein

, I60L, S68N, S103P, L121M, V127A, D128G, N152T

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First mention in abstract form: 2004 Flegel WA & et al. Blood (ASH Annual Meeting Abstracts) 2004 104: Abstract 2706

First full publication: 2009 Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71. (submitted 2008-05-23)

ISBT group

RHD negative

Phenotype characterization and grouping

D negative

Serology

D negative Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71.

Observations

South-Western Germany: Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71.

Additional comments

Characterization was based on PCR pattern, the hybrid structure is putative.

Last update: 2017-06-06 (yyyy-MM-dd)