| Designation | ISBT name | Cluster | Haplotype | Mechanism | Alterations | First mention | Definitive publication |
| D-SPM | RHD*40 RHD*D-SPM | DIVa cluster | cDe | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V) | 2012 | |
| DAR(CE2:V50V-S68N) | RHD*09.06 RHD*DAR6 RHD*DAR(SE2:v50V-S68N) | weak D type 4 cluster | cDe | Complex changes | 1025T>C (I342T) 150T>C 178A>C (I60L) 201G>A 203G>A (S68N) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2013 | |
| DAR(T203A) | RHD*09.01 RHD*DAR | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 607A>G (T203A) 667T>G (F223V) 744C>T 957 G>A | 2012 | 2012 |
| DAR-E | RHD*09.02 RHD*DAR2 | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 957 G>A | 2006 | 2006 |
| DAR1 (weak D type 4.2.0) | RHD*09.01.00 RHD*DAR1.00 | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) | 1998 | 1999 |
| DAR2.1 | RHD*09.02.01 RHD*DAR2.01 | weak D type 4 cluster | not reported | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 744C>T 957 G>A | ||
| DAU-0 | RHD*10.00 RHD*DAU0 | DAU cluster | cDe | Single missense mutation | 1136C>T (T379M) | 2002 | 2002 |
| DAU-1 | RHD*10.01 RHD*DAU1 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 689G>T (S230I) | 2002 | 2002 |
| DAU-2 | RHD*10.02 RHD*DAU2 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 209G>A (R70Q) 998G>A (S333N) | 2002 | 2002 |
| DAU-3 | RHD*10.03 RHD*DAU3 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 835G>A (V279M) | 2002 | 2002 |
| DAU-4 | RHD*10.04 RHD*DAU4 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 697G>A (E233K) | 2002 | 2002 |
| DAU-5 | RHD*10.05 RHD*DAU5 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q) | 2005 | 2005 |
| DAU-6 | RHD*10.06 RHD*DAU6 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 998G>A (S333N) | 2005 | 2005 |
| DAU-7 | RHD*10.07 RHD*DAU7 | DAU cluster | cDe | Single missense mutation | 1136C>T (T379M) 835G>A (V279M) 998G>A (S333N) | 2009 | 2009 |
| DBS-0 | RHD*05.03 RHD*DV.3 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHcE[226P](5:667-5:712) | 1996 | 1996 |
| DBS-1 | RHD*13.01 RHD*DBS1 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](5:667-5:800) | 2001 | 2001 |
| DBS-2 | RHD*13.02 RHD*DBS2 RHD*16.03 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](5:667-5:697) | 2009 | 2012 |
| DBT-1 | RHD*14.01 RHD*DBT1 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5-7) | 1996 | 1996 |
| DBT-2 | RHD*14.02 RHD*DBT2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5-9) | 1999 | 1999 |
| DBU | RHD*41 RHD*DBU RHD*01EL.23 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](5-7) | 2008 | 2009 |
| DCC | RHD*42 RHD*DCC | Eurasian D cluster | CDe | Single missense mutation | 677C>A (A226D) | 2007 | 2012 |
| DCS-1 | RHD*16.01 RHD*DCS1 | Eurasian D cluster | cDE | hybrid allele | 667T>G (F223V) 676G>C (A226P) | 1999 | 2008 |
| DCS-2 | RHD*16.02 RHD*DCS2 | Eurasian D cluster | cDE | Single missense mutation | 676G>C (A226P) | 2008 | 2008 |
| DDE | RHD*27 RHD*DDE | Eurasian D cluster | not reported | Single missense mutation | 120T>A (D40E) | 2007 | |
| DDN | RHD*43 RHD*DDN | Eurasian D cluster | not reported | Single missense mutation | 490G>A (D164N) | 2008 | |
| DFL | RHD*28 RHD*DFL | Eurasian D cluster | CDe | Single missense mutation | 494A>G (Y165C) | 2005 | 2007 |
| DFR-1 | RHD*17.01 RHD*DFR1 | Eurasian D cluster | multiple | hybrid allele | Hybrid RHCE(4:505-4:514) | 1995 | 1995 |
| DFR-2 | RHD*17.02 RHD*DFR2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(4) | 1997 | 1997 |
| DFR-3 | RHD*17.03 RHD*DFR3 | Eurasian D cluster | CDe | Complex changes | 539G>C (G180A) Hybrid RHCE(4:505-4:514) | 2007 | 2007 |
| DFR-4 | RHD*17.04 RHD*DFR4 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(4:505-4:509) | 2009 | 2012 |
| DFR-5 | RHD*17.05 RHD*DFR5 | Eurasian D cluster | not reported | hybrid allele | Hybrid RHCE(3-4) | 2007 | |
| DFV | RHD*08.01 RHD*DFV | weak D type 4 cluster | multiple | Single missense mutation | 667T>G (F223V) | 2002 | 2002 |
| DFW | RHD*18 RHD*DFW | Eurasian D cluster | CDe | Single missense mutation | 497A>C (H166P) | 1998 | 2009 |
| DHAR | Eurasian D cluster | cde | hybrid allele | Hybrid RHCE(1-4) Hybrid RHCE(6-10) | 1996 | 1996 | |
| DHK | RHD*05.05 RHD*DV.5 | Eurasian D cluster | CDe | Single missense mutation | 697G>A (E233K) | 1998 | 1999 |
| DHMi | RHD*19 RHD*DHMi | Eurasian D cluster | cDE | Single missense mutation | 848C>T (T283I) | 1996 | |
| DHMii | Eurasian D cluster | cDE | hybrid allele | 1996 | |||
| DHO | RHD*20 RHD*DHO | Eurasian D cluster | CDe | Single missense mutation | 704A>C (K235T) | 2001 | 2001 |
| DHQ | RHD*44 RHD*DHQ | Eurasian D cluster | not reported | Single missense mutation | 513C>A (H171Q) | 2004 | |
| DHR | RHD*22 RHD*DHR | Eurasian D cluster | not reported | Single missense mutation | 686G>A (R229K) | 1997 | 1997 |
| DII | RHD*02 RHD*DII | Eurasian D cluster | CDe | Single missense mutation | 1061C>A (A354D) | 1997 | 1997 |
| DIII type 4 | RHD*03.04 RHD*DIII.4 | DIVa cluster | CDe | hybrid allele | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2000 | 2000 |
| DIII type 5 | RHD*03.01 RHD*DIIIa | DIVa cluster | cDe | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | ||
| DIII type 6 | RHD*03.06 RHD*DIII.6 | DIVa cluster | cDe | Multiple missense mutations | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2005 | 2006 |
| DIII type 7 | RHD*03.07 RHD*DIII.07 | DIVa cluster | cDe | Complex changes | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A Hybrid RHCE(2) | 2005 | 2006 |
| DIII type 8 | RHD*03.08 RHD*DIII.08 | DIVa cluster | not reported | Multiple missense mutations | 410C>T (A137V) 455A>C (N152T) | 2010 | |
| DIII type 9 | RHD*03.09 RHD*DIII.09 | DIVa cluster | not reported | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 667T>G (F223V) | ||
| DIIIc | RHD*03.03 RHD*DIIIc | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3) | 1996 | 1996 |
| DIM | RHD*34 RHD*DIM | Eurasian D cluster | cDE | Single missense mutation | 854G>A (C285Y) | 2000 | 2000 |
| DIV type 1.0 | RHD*04.01 RHD*DIVa. | DIVa cluster | cDe | Multiple missense mutations | 1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2012 | |
| DIV type 3 | RHD*04.03 RHD* DIV.3 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(6-9) | 1999 | 1999 |
| DIV type 4 | RHD*04.04 RHD*DIV.4 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(7:1048-7:1061) | 1998 | |
| DIV type 5 | RHD*04.05 RHD*DIV.5 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHCE(7-9) | 2000 | 2000 |
| DIVb type 2 | RHD*04.06 RHD* DIVb | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(7:1048-9) | 1995 | 1995 |
| DKG | Eurasian D cluster | not reported | large deletion | 25321477_25322488del | 2017 | 2017 | |
| DKK | RHD*45 RHD*DKK | Eurasian D cluster | cDE | hybrid allele | Hybrid RHCE(2-3) | 2000 | 2001 |
| DLO | RHD*36 RHD*DLO | Eurasian D cluster | not reported | Single missense mutation | 851C>T (S284L) | 2003 | 2004 |
| DLX | RHD*46 RHD*DLX | Eurasian D cluster | cDE | Complex changes | 667T>G (F223V) Hybrid RHCE(5:712-6) | 2012 | 2012 |
| DMH | RHD*23 RHD*DMH | Eurasian D cluster | cDe | Missense (splice site affected) | 161T>C (L54P) | 1999 | |
| DMI | RHD*47 RHD*DMI | Eurasian D cluster | CDe | Single missense mutation | 510G>A (M170I) | 2008 | 2009 |
| DMI-1.1 | RHD*47.01 RHD*DMI-1.1 | Eurasian D cluster | CDe | Single missense mutation | 510G>T (M170I) | 2010 | |
| DNAK | RHD*24 RHD*DNAK | Eurasian D cluster | cDE | Single missense mutation | 1070G>A (G357D) | 2005 | |
| DNB | RHD*25 RHD*DNB | Eurasian D cluster | CDe | Single missense mutation | 1063G>A (G355S) | 2002 | 2002 |
| DNS | RHD*48 RHD*DNS | Eurasian D cluster | not reported | Single missense mutation | 485A>G (N162S) | 2006 | |
| DNT | Eurasian D cluster | CDe | Single missense mutation | 455A>C (N152T) | 2009 | 2013 | |
| DNU | RHD*26 RHD*DNU | Eurasian D cluster | cDE | Single missense mutation | 1057G>A (G353R) | 1997 | 1997 |
| DOL-1 | RHD*12.01 RHD*DOL1 | weak D type 4 cluster | cDe | Multiple missense mutations | 509T>C (M170T) 667T>G (F223V) | 1999 | 2009 |
| DOL-2 | RHD*12.02 RHD*DOL2 | weak D type 4 cluster | not reported | Multiple missense mutations | 1132C>G (L378V) 509T>C (M170T) 667T>G (F223V) | 2005 | 2009 |
| DOL-3 | RHD*12.03 RHD*DOL3 | weak D type 4 cluster | not reported | Multiple missense mutations | 410C>T (A137V) 509T>C (M170T) 667T>G (F223V) | 2005 | |
| DOL-4 | RHD*12.04 RHD*DOL4 | DIVa cluster | not reported | hybrid allele | 410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V) | ||
| DTO | RHD*30 RHD*DTO | weak D type 4 cluster | not reported | Multiple missense mutations | 667T>G (F223V) 674C>T (S225F) | 2005 | 2005 |
| DV type 1 | RHD*05.01 RHD*DV.1 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:697) | 1995 | 1995 |
| DV type 10 | RHD*05.10 RHD*DV.10 | Eurasian D cluster | not reported | hybrid allele | Hybrid RHCE(5-6) | ||
| DV type 2 | RHD*05.02 RHD*DV.2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5) | 1995 | 1995 |
| DV type 4 | RHD*05.04 RHD*DV.4 | Eurasian D cluster | CDe | Single missense mutation | 697G>C (E233Q) | 1998 | 1999 |
| DV type 6 | RHD*05.06 RHD*DV.6 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:712) | 1998 | 1999 |
| DV type 7 | RHD*05.07 RHD*DV.7 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:787) | 2001 | 2001 |
| DV type 8 | RHD*05.08 RHD*DV.8 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:744) | 1998 | 1999 |
| DV type 9 | RHD*05.09 RHD*DV.9 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:697-5:712) | 1999 | 2000 |
| DVI type 1 | RHD*06.01 RHD*DVI.1 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](4-5) | 1997 | 1997 |
| DVI type 2 | RHD*06.02 RHD*DVI.2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(4-6) | 1994 | 1994 |
| DVI type 3 | RHD*06.03 RHD*DVI.3 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3-6) | 1998 | 1998 |
| DVI type 3.2 | RHD*06.03.02 RHD*DVI.03.02 | Eurasian D cluster | not reported | hybrid allele | 1195G>A (A399T) Hybrid RHCE(3-6) | ||
| DVI type 4 | RHD*06.04 RHD*DVI.4 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3-5) | 2000 | 2006 |
| DVII | RHD*07.01 RHD*DVII.1 | Eurasian D cluster | CDe | Single missense mutation | 329T>C (L110P) | 1995 | 1995 |
| DVII type 2 | RHD*07.02 RHD*DVII.2 | Eurasian D cluster | CDe | Multiple missense mutations | 307T>C (S103P) 329T>C (L110P) | 2001 | 2001 |
| DVL-1 | RHD*31 RHD*DVL1 | Eurasian D cluster | not reported | In frame deletion | 684delGAG (229delR) | 2004 | 2006 |
| DVL-2 | RHD*32 RHD*DVL2 | Eurasian D cluster | not reported | In frame deletion | 705delGAA (235delK) | 2006 | 2006 |
| DWI | RHD*33 RHD*DWI | Eurasian D cluster | CDe | Single missense mutation | 1073T>C (M358T) | 2004 | 2004 |
| DWN | RHD*49 RHD*DWN | Eurasian D cluster | cDe | hybrid allele | Hybrid RHCE(7:1053-7:1061) | 2013 | 2013 |
| DYU | RHD*29 RHD*DYU | Eurasian D cluster | cDe | Single missense mutation | 700A>T (R234W) | 2003 | 2005 |
| RHCE(5:697-5:744)-RHD | Eurasian D cluster | not reported | hybrid allele | Hybrid RHCE(5:697-5:744) | 2018 | 2018 | |
| RHD(A354T) | RHD*50 | Eurasian D cluster | CDe | Single missense mutation | 1060G>A (A354T) | 2014 | 2014 |
| RHD(D164E) | RHD*61 | Eurasian D cluster | not reported | Single missense mutation | 492C>A (D164E) | ||
| RHD(del44L) | RHD*51 | Eurasian D cluster | not reported | In frame deletion | 130delCTC | 2013 | 2014 |
| RHD(F175L) | RHD*59 | Eurasian D cluster | not reported | Single missense mutation | 525C>A (F175L) | 2012 | 2012 |
| RHD(IVS2-2delA) | RHD*53 RHD*01EL.22 | Eurasian D cluster | not reported | Short deletion | IVS2-2delA | 2013 | |
| RHD(IVS4-2A>C) | RHD*54 | Eurasian D cluster | cDE | Splice site mutation | IVS4-2A>C | 2014 | 2014 |
| RHD(L214F)-CE(7)-D | Eurasian D cluster | not reported | Single missense mutation | 640C>T (L214F) Hybrid RHCE(7) | 2018 | 2018 | |
| RHD(L81P) | RHD*55 | Eurasian D cluster | not reported | Single missense mutation | 242T>C (L81P) | 2009 | |
| RHD(M118K,V174M) | Eurasian D cluster | not reported | Multiple missense mutations | 353T>A (M118K) 520G>A (V174M) | 2017 | 2017 | |
| RHD(M295I) | RHD*11 RHD*weak partial 11 | Eurasian D cluster | CDe | Single missense mutation | 885G>T (M295I) | 2001 | 2001 |
| RHD(S103P) | RHD*39 | Eurasian D cluster | cDE | Single missense mutation | 307T>C (S103P) | 1996 | 1996 |
| RHD(T201R)-CE(5)-D(I342T) | weak D type 4 cluster | not reported | Complex changes | 1025T>C (I342T) 602C>G (T201R) Hybrid RHCE(5) | 2018 | 2018 | |
| RHD-RHCE(7)-RHD | RHD*58 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHCE(7) | 2012 | |
| weak D type 11 | RHD*11 RHD*weak partial 11 | Eurasian D cluster | cDe | Single missense mutation | 885G>T (M295I) | 1999 | 1999 |
| weak D type 141 | RHD*52 RHD* 01W.141 | Eurasian D cluster | cDe | Single missense mutation | 668T>C (F223S) | 2015 | 2016 |
| weak D type 15 | RHD*15 RHD*weak partial 15 | Eurasian D cluster | cDE | Single missense mutation | 845G>A (G282D) | 1999 | 1999 |
| weak D type 21 | RHD*21 RHD*weak partial D 21 | Eurasian D cluster | CDe | Single missense mutation | 938C>T (P313L) | 2001 | 2001 |
| weak D type 4.0 | RHD*09.03.01 RHD*DAR3 | weak D type 4 cluster | cDe | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A | 1999 | 1999 |
| weak D type 4.0.1 | RHD*09.03 RHD*DAR3 | weak D type 4 cluster | cDe | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) | ||
| weak D type 4.2.1 (DAR1.1) | RHD*09.01.01 RHD*DAR1.01 RHD*weak 4.2 | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2000 | 2000 |
| weak D type 4.2.2 (DAR1.2) | RHD*09.01.02 | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T 957 G>A | 2000 | 2000 |
| weak D type 4.2.3 (DAR1.3) | RHD*09.01.03 RHD*DAR1.03 | weak D type 4 cluster | cDe | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T | 2008 | |
| weak D type 4.3 | RHD*09. 05 RHD*weak 4.3 | weak D type 4 cluster | cDe | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A 872C>G (P291R) | 2004 | |
| weak D type 42 | RHD*01W.42 RHD*weak D type 42 | Eurasian D cluster | not reported | Missense (splice site affected) | 1226A>T (K409M) | 2005 | 2005 |
| weak D type 45 | RHD*01W.45 RHD*weak D type 45 | Eurasian D cluster | not reported | Single missense mutation | 1195G>A (A399T) | 2004 | |
| weak D type 57 | RHD*57 RHD*weak partial 57 | Eurasian D cluster | not reported | Single missense mutation | 640C>T (L214F) | 2007 | 2007 |