DIII type 4

Structure

RHD(L62F,A137V,N152T)

Key changes from standard allele

186G>T (L62F)
410C>T (A137V)
455A>C (N152T)

ISBT allele designation

RHD*03.04
RHD*DIII.4

Nucleotide changes relative to "standard RHD"

c.[186 G>T;410 C>T;455 A>C]

Amino acid changes relative to standard protein

L62F, A137V, N152T

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D; D category

Haplotype (typical)

CDe

Allele cluster

DIVa cluster

Descriptions

First full publication: 2000 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708. (submitted 1999-08-13)

Serology

Rhesus Index 0.45 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.
Rhesus immunization registry: anti-D 1:16

Observations

No data

Related Alleles

Ccdes-1 [RHD(L62F,A137V,N152T)-RHCE(4-7)-RHD(G336C)]
D-SPM [RHD(L62F,A137V,N152T,M170T,F223V)]
DIII type 4.2 [RHD(L62F,S103P,A137V,N152T)]
DIII type 5 [RHD(L62F,A137V,N152T,T201R,F223V)]
DIII type 9 [RHD(L62F,A137V,N152T,F223V)]
DIIIa150C [RHD(150T>C,L62F,A137V,N152T,T201R,F223V,819G>A)]
DIV(S103P) [RHD(L62F,S103P,A137V,N152T)]
DIV-DOL [RHD(L62F,A137V,N152T,M170T,F223V)]
DIV type 1.0 [RHD(L62F,A137V,N152T,D350H)]
DIVa-like [RHD(L62F,A137V,N152T,F223V,D350H)]

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)