partial RHD

according to ISBT allele nomenclature version v5.0 (07-Feb-2018)

Designation	ISBT name	Cluster	Haplotype	Mechanism	Alterations	First mention	Definitive publication
DAU-0.1	RHD10.00.01 RHDDAU0.01	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 579G>A	2003	2003
RHD(M1_S2insV,T379M)		DAU cluster	not reported	Complex changes	1136C>T (T379M) 3_4insGTG (M1_S2insV)	2008
weak D type 4.0.1	RHD09.03 RHDDAR3	weak D type 4 cluster	cDe	Multiple missense mutations	602C>G (T201R) 667T>G (F223V)
weak D type 57	RHD57 RHDweak partial 57	Eurasian D cluster	not reported	Single missense mutation	640C>T (L214F)	2007	2007
DII	RHD02 RHDDII	Eurasian D cluster	CDe	Single missense mutation	1061C>A (A354D)	1997	1997
DIII type 5	RHD03.01 RHDDIIIa	DIVa cluster	cDe	Multiple missense mutations	186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A
DIIIc	RHD03.03 RHDDIIIc	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(3)	1996	1996
DIII type 4	RHD03.04 RHDDIII.4	DIVa cluster	CDe	hybrid allele	186G>T (L62F) 410C>T (A137V) 455A>C (N152T)	2000	2000
DIII type 4.2	RHD03.04.02 RHDDII.04.02	Eurasian D cluster	not reported	hybrid allele	186G>T (L62F) 307T>C (S103P) 410C>T (A137V) 455A>C (N152T)
DIII type 6	RHD03.06 RHDDIII.6	DIVa cluster	cDe	Multiple missense mutations	410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A	2005	2006
DIII type 7	RHD03.07 RHDDIII.07	DIVa cluster	cDe	Complex changes	410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A Hybrid RHCE(2)	2005	2006
DIII type 8	RHD03.08 RHDDIII.08	DIVa cluster	not reported	Multiple missense mutations	410C>T (A137V) 455A>C (N152T)	2010
DIV type 1.0	RHD04.01 RHDDIVa.	DIVa cluster	cDe	Multiple missense mutations	1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T)	2012
DIVa-like	RHD*04.01.02	Eurasian D cluster	not reported	hybrid allele	1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 667T>G (F223V)
DIV type 3	RHD04.03 RHD DIV.3	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(6-9)	1999	1999
DIV type 4	RHD04.04 RHDDIV.4	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(7:1048-7:1061)	1998
DIV type 5	RHD04.05 RHDDIV.5	Eurasian D cluster	cDE	hybrid allele	Hybrid RHCE(7-9)	2000	2000
DIVb type 2	RHD04.06 RHD DIVb	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(7:1048-9)	1995	1995
DV type 1	RHD05.01 RHDDV.1	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5:667-5:697)	1995	1995
DV type 2	RHD05.02 RHDDV.2	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5)	1995	1995
DBS-0	RHD05.03 RHDDV.3	Eurasian D cluster	CDe	hybrid allele	Hybrid RHcE[226P](5:667-5:712)	1996	1996
DV type 4	RHD05.04 RHDDV.4	Eurasian D cluster	CDe	Single missense mutation	697G>C (E233Q)	1998	1999
DHK	RHD05.05 RHDDV.5	Eurasian D cluster	CDe	Single missense mutation	697G>A (E233K)	1998	1999
DV type 6	RHD05.06 RHDDV.6	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5:667-5:712)	1998	1999
DV type 7	RHD05.07 RHDDV.7	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5:667-5:787)	2001	2001
DV type 8	RHD05.08 RHDDV.8	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5:667-5:744)	1998	1999
DV type 9	RHD05.09 RHDDV.9	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5:697-5:712)	1999	2000
DV type 10	RHD05.10 RHDDV.10	Eurasian D cluster	not reported	hybrid allele	Hybrid RHCE(5-6)
DVI type 1	RHD06.01 RHDDVI.1	Eurasian D cluster	cDE	hybrid allele	Hybrid RHcE[226P](4-5)	1997	1997
DVI type 2	RHD06.02 RHDDVI.2	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(4-6)	1994	1994
DVI type 3	RHD06.03 RHDDVI.3	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(3-6)	1998	1998
DVI type 3.2	RHD06.03.02 RHDDVI.03.02	Eurasian D cluster	not reported	hybrid allele	1195G>A (A399T) Hybrid RHCE(3-6)
DVI type 4	RHD06.04 RHDDVI.4	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(3-5)	2000	2006
DVII	RHD07.01 RHDDVII.1	Eurasian D cluster	CDe	Single missense mutation	329T>C (L110P)	1995	1995
DVII type 2	RHD07.02 RHDDVII.2	Eurasian D cluster	CDe	Multiple missense mutations	307T>C (S103P) 329T>C (L110P)	2001	2001
DFV	RHD08.01 RHDDFV	weak D type 4 cluster	multiple	Single missense mutation	667T>G (F223V)	2002	2002
DAR(T203A)	RHD09.01 RHDDAR	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 607A>G (T203A) 667T>G (F223V) 744C>T 957 G>A	2012	2012
DAR1 (weak D type 4.2.0)	RHD09.01.00 RHDDAR1.00	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V)	1998	1999
weak D type 4.2.1 (DAR1.1)	RHD09.01.01 RHDDAR1.01 RHD*weak 4.2	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 957 G>A	2000	2000
weak D type 4.2.2 (DAR1.2)	RHD*09.01.02	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T 957 G>A	2000	2000
weak D type 4.2.3 (DAR1.3)	RHD09.01.03 RHDDAR1.03	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T	2008
DAR-E	RHD09.02 RHDDAR2	weak D type 4 cluster	cDe	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 957 G>A	2006	2006
DAR2.1	RHD09.02.01 RHDDAR2.01	weak D type 4 cluster	not reported	Multiple missense mutations	1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 744C>T 957 G>A
weak D type 4.0	RHD09.03.01 RHDDAR3	weak D type 4 cluster	cDe	Multiple missense mutations	602C>G (T201R) 667T>G (F223V) 819G>A	1999	1999
weak D type 4.1	RHD09.04 RHDDAR4	weak D type 4 cluster	cDe	Multiple missense mutations	48G>C (W16C) 602C>G (T201R) 667T>G (F223V) 819G>A	2000	2000
weak D type 4.3	RHD09. 05 RHDweak 4.3	weak D type 4 cluster	cDe	Multiple missense mutations	602C>G (T201R) 667T>G (F223V) 819G>A 872C>G (P291R)	2004
DAR(CE2:V50V-S68N)	RHD09.06 RHDDAR6 RHD*DAR(SE2:v50V-S68N)	weak D type 4 cluster	cDe	Complex changes	1025T>C (I342T) 150T>C 178A>C (I60L) 201G>A 203G>A (S68N) 602C>G (T201R) 667T>G (F223V) 957 G>A	2013
DAU-0	RHD10.00 RHDDAU0	DAU cluster	cDe	Single missense mutation	1136C>T (T379M)	2002	2002
DAU-0.2	RHD10.00.02 RHDDAU0.02	Eurasian D cluster	not reported	Complex changes	1136C>T (T379M) 150T>C
DAU-1	RHD10.01 RHDDAU1	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 689G>T (S230I)	2002	2002
DAU-2	RHD10.02 RHDDAU2	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 209G>A (R70Q) 998G>A (S333N)	2002	2002
DAU-3	RHD10.03 RHDDAU3	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 835G>A (V279M)	2002	2002
DAU-4	RHD10.04 RHDDAU4	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 697G>A (E233K)	2002	2002
DAU-5	RHD10.05 RHDDAU5	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q)	2005	2005
DAU-5.1	RHD10.05.01 RHDDAU5.01	DAU cluster	cDe	Multiple missense mutations	1122C>T (I374I) 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q)	2014	2016
DAU-6	RHD10.06 RHDDAU6	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 998G>A (S333N)	2005	2005
DAU-7	RHD10.07 RHDDAU7	DAU cluster	cDe	Single missense mutation	1136C>T (T379M) 835G>A (V279M) 998G>A (S333N)	2009	2009
DAU-8	RHD10.08 RHDDAU8	DAU cluster	not reported	Multiple missense mutations	1136C>T (T379M) 340C>T (R114W) 579G>A	2012	2012
DAU-9	RHD10.09 RHDDAU9	DAU cluster	not reported	Multiple missense mutations	1136C>T (T379M) 535T>C (F179L)	2012	2012
DAU-10	RHD10.10 RHDDAU10	DAU cluster	not reported	Multiple missense mutations	1136C>T (T379M) 579G>A 739G>C (V247L)	2012	2012
DAU-11	RHD10.11 RHDDAU11	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 254C>T (A85V) 835G>A (V279M)	2012	2016
DAU-12	RHD10.12 RHDDAU12	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 542T>C (L181P)	2012
DAU-13	RHD10.13 RHDDAU13	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 48G>C (W16C)	2013
DAU-14	RHD10.14 RHDDAU14	DAU cluster	cDe	Multiple missense mutations	1136C>T (T379M) 201G>A 203G>A (S68N)	2014	2014
RHD(M1V,T379M)	RHD10.15 RHDDAU15	DAU cluster	not reported	Complex changes	1136C>T (T379M) 1A>G (M1?)	2008
RHD(M295I)	RHD11 RHDweak partial 11	Eurasian D cluster	CDe	Single missense mutation	885G>T (M295I)	2001	2001
weak D type 11	RHD11 RHDweak partial 11	Eurasian D cluster	cDe	Single missense mutation	885G>T (M295I)	1999	1999
DOL-1	RHD12.01 RHDDOL1	weak D type 4 cluster	cDe	Multiple missense mutations	509T>C (M170T) 667T>G (F223V)	1999	2009
DOL-2	RHD12.02 RHDDOL2	weak D type 4 cluster	not reported	Multiple missense mutations	1132C>G (L378V) 509T>C (M170T) 667T>G (F223V)	2005	2009
DOL-3	RHD12.03 RHDDOL3	weak D type 4 cluster	not reported	Multiple missense mutations	410C>T (A137V) 509T>C (M170T) 667T>G (F223V)	2005
DOL-4	RHD12.04 RHDDOL4	DIVa cluster	not reported	hybrid allele	410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V)
DBS-1	RHD13.01 RHDDBS1	Eurasian D cluster	cDE	hybrid allele	Hybrid RHcE[226P](5:667-5:800)	2001	2001
DBS-2	RHD13.02 RHDDBS2 RHD16.03 RHDDCS3	Eurasian D cluster	cDE	hybrid allele	Hybrid RHcE[226P](5:667-5:697)	2009	2012
DBT-1	RHD14.01 RHDDBT1	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5-7)	1996	1996
DBT-2	RHD14.02 RHDDBT2	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(5-9)	1999	1999
weak D type 15	RHD15 RHDweak partial 15	Eurasian D cluster	cDE	Single missense mutation	845G>A (G282D)	1999	1999
DCS-1	RHD16.01 RHDDCS1	Eurasian D cluster	cDE	hybrid allele	667T>G (F223V) 676G>C (A226P)	1999	2008
DCS-2	RHD16.02 RHDDCS2	Eurasian D cluster	cDE	Single missense mutation	676G>C (A226P)	2008	2008
DFR-1	RHD17.01 RHDDFR1	Eurasian D cluster	multiple	hybrid allele	Hybrid RHCE(4:505-4:514)	1995	1995
DFR-2	RHD17.02 RHDDFR2	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(4)	1997	1997
DFR-3	RHD17.03 RHDDFR3	Eurasian D cluster	CDe	Complex changes	539G>C (G180A) Hybrid RHCE(4:505-4:514)	2007	2007
DFR-4	RHD17.04 RHDDFR4	Eurasian D cluster	CDe	hybrid allele	Hybrid RHCE(4:505-4:509)	2009	2012
DFR-5	RHD17.05 RHDDFR5	Eurasian D cluster	not reported	hybrid allele	Hybrid RHCE(3-4)	2007
DFW	RHD18 RHDDFW	Eurasian D cluster	CDe	Single missense mutation	497A>C (H166P)	1998	2009
DHMi	RHD19 RHDDHMi	Eurasian D cluster	cDE	Single missense mutation	848C>T (T283I)	1996
DHO	RHD20 RHDDHO	Eurasian D cluster	CDe	Single missense mutation	704A>C (K235T)	2001	2001
weak D type 21	RHD21 RHDweak partial D 21	Eurasian D cluster	CDe	Single missense mutation	938C>T (P313L)	2001	2001
DHR	RHD22 RHDDHR	Eurasian D cluster	not reported	Single missense mutation	686G>A (R229K)	1997	1997
DMH	RHD23 RHDDMH	Eurasian D cluster	cDe	Missense (splice site affected)	161T>C (L54P)	1999
DNAK	RHD24 RHDDNAK	Eurasian D cluster	cDE	Single missense mutation	1070G>A (G357D)	2005
DNB	RHD25 RHDDNB	Eurasian D cluster	CDe	Single missense mutation	1063G>A (G355S)	2002	2002
DNU	RHD26 RHDDNU	Eurasian D cluster	cDE	Single missense mutation	1057G>A (G353R)	1997	1997
DDE	RHD27 RHDDDE	Eurasian D cluster	not reported	Single missense mutation	120T>A (D40E)	2007
DFL	RHD28 RHDDFL	Eurasian D cluster	CDe	Single missense mutation	494A>G (Y165C)	2005	2007
DYU	RHD29 RHDDYU	Eurasian D cluster	cDe	Single missense mutation	700A>T (R234W)	2003	2005
DTO	RHD30 RHDDTO	weak D type 4 cluster	not reported	Multiple missense mutations	667T>G (F223V) 674C>T (S225F)	2005	2005
DVL-1	RHD31 RHDDVL1	Eurasian D cluster	not reported	In frame deletion	684delGAG (229delR)	2004	2006
DVL-2	RHD32 RHDDVL2	Eurasian D cluster	not reported	In frame deletion	705delGAA (235delK)	2006	2006
DWI	RHD33 RHDDWI	Eurasian D cluster	CDe	Single missense mutation	1073T>C (M358T)	2004	2004
DIM	RHD34 RHDDIM	Eurasian D cluster	cDE	Single missense mutation	854G>A (C285Y)	2000	2000
DMA	RHD35 RHDDMA	Eurasian D cluster	cDe	Single missense mutation	621G>C (L207F)	2003	2003
DLO	RHD36 RHDDLO	Eurasian D cluster	not reported	Single missense mutation	851C>T (S284L)	2003	2004
DUC-2	RHD37 RHDDUC2	Eurasian D cluster	not reported	Single missense mutation	733G>C (V245L)	2005	2005
RHD(S103P)	RHD*39	Eurasian D cluster	cDE	Single missense mutation	307T>C (S103P)	1996	1996
D-SPM	RHD40 RHDD-SPM	DIVa cluster	cDe	Multiple missense mutations	186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V)	2012
DBU	RHD41 RHDDBU RHD01EL.23 RHDDEL23	Eurasian D cluster	cDE	hybrid allele	Hybrid RHcE[226P](5-7)	2008	2009
DCC	RHD42 RHDDCC	Eurasian D cluster	CDe	Single missense mutation	677C>A (A226D)	2007	2012
DDN	RHD43 RHDDDN	Eurasian D cluster	not reported	Single missense mutation	490G>A (D164N)	2008
DHQ	RHD44 RHDDHQ	Eurasian D cluster	not reported	Single missense mutation	513C>A (H171Q)	2004
DKK	RHD45 RHDDKK	Eurasian D cluster	cDE	hybrid allele	Hybrid RHCE(2-3)	2000	2001
DLX	RHD46 RHDDLX	Eurasian D cluster	cDE	Complex changes	667T>G (F223V) Hybrid RHCE(5:712-6)	2012	2012
DMI	RHD47 RHDDMI	Eurasian D cluster	CDe	Single missense mutation	510G>A (M170I)	2008	2009
DMI-1.1	RHD47.01 RHDDMI-1.1	Eurasian D cluster	CDe	Single missense mutation	510G>T (M170I)	2010
DNS	RHD48 RHDDNS	Eurasian D cluster	not reported	Single missense mutation	485A>G (N162S)	2006
DWN	RHD49 RHDDWN	Eurasian D cluster	cDe	hybrid allele	Hybrid RHCE(7:1053-7:1061)	2013	2013
RHD(A354T)	RHD*50	Eurasian D cluster	CDe	Single missense mutation	1060G>A (A354T)	2014	2014
RHD(del44L)	RHD*51	Eurasian D cluster	not reported	In frame deletion	130delCTC	2013	2014
weak D type 141	RHD52 RHD 01W.141 RHD*weak D type 141	Eurasian D cluster	cDe	Single missense mutation	668T>C (F223S)	2015	2016
RHD(IVS2-2delA)	RHD53 RHD01EL.22 RHD*DEL22	Eurasian D cluster	not reported	Short deletion	IVS2-2delA	2013
RHD(IVS4-2A>C)	RHD*54	Eurasian D cluster	cDE	Splice site mutation	IVS4-2A>C	2014	2014
RHD(L81P)	RHD*55	Eurasian D cluster	not reported	Single missense mutation	242T>C (L81P)	2009
DBA	RHD56 RHDDBA	Eurasian D cluster	not reported	Single missense mutation	680T>C (L227P)	2003	2004
RHD-RHCE(7)-RHD	RHD*58	Eurasian D cluster	cDE	hybrid allele	Hybrid RHCE(7)	2012
RHD(F175L)	RHD*59	Eurasian D cluster	not reported	Single missense mutation	525C>A (F175L)	2012	2012
RHD(60L,S230I)	RHD*60	Eurasian D cluster	not reported	Single missense mutation	178A>C (I60L) 689G>T (S230I)
RHD(D164E)	RHD*61	Eurasian D cluster	not reported	Single missense mutation	492C>A (D164E)
RHD(N152T,V270G)	RHD*62	Eurasian D cluster	not reported	Multiple missense mutations	455A>C (N152T) 809T>G (V270G)	2014