Note: This is a mixed bag of structures for which I didn't find a proposed ISBT name at the time of entering. It may include non-existent structures, existent structures considered obsolete by the ISBT, structures overlooked by ISBT, recently described structures, and structures for which I just didn't find the time to enter the proposed ISBT name.
Designation | Haplotype | Phenotype | Cluster | Structure | First mention | Definitive publication |
D186T | not reported | DIVa cluster | RHD(L62F) | 2012 | ||
DIIIa150C | not reported | DIVa cluster | RHD(150T>C,L62F,A137V,N152T,T201R,F223V,819G>A) | 2012 | ||
RHD(147A>G) | not reported | Eurasian D cluster | RHD(147A>G) | 2011 | 2012 | |
RHD(1347A>G) | cDe | Eurasian D cluster | RHD(1347A>G) | 2003 | 2003 | |
RHD(27del13) | not reported | Eurasian D cluster | RHD(27del13) | 2012 | ||
RHD(29del14) | not reported | weakened D expression | Eurasian D cluster | RHD(29del14) | 2012 | 2012 |
see DFV | ||||||
D674 | not reported | Eurasian D cluster | RHD(S225F) | 2002 | 2002 | |
see DV type 7 | ||||||
see RHD(165C>T) | ||||||
DBO-2 | not reported | weakened D expression | Eurasian D cluster | RHD(357T>C) | 2006 | |
DBO-3 | not reported | Eurasian D cluster | RHD(P323H) | 2006 | ||
see DBS-2 | ||||||
see weak D type 38 | ||||||
DFV.1 | cDe | weakened D expression | weak D type 4 cluster | RHD(F223V) | 2013 | 2014 |
DHAR | cde | Partial D | Eurasian D cluster | RHCE-RHD(5)-RHCE | 1996 | 1996 |
DHMii | cDE | Partial D | Eurasian D cluster | 1996 | ||
see DIII type 5 | ||||||
DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D | not reported | DIVa cluster | DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D | 2017 | ||
see DIII type 7 | ||||||
DIT-1 | CDe | weakened D expression | Eurasian D cluster | RHD(I288T) | 2005 | |
DIT-2 | CDe | weakened D expression | Eurasian D cluster | RHD(I288F) | 2011 | |
DIV(S103P) | cDe | DIVa cluster | RHD(L62F,S103P,A137V,N152T) | 2013 | ||
see D-SPM | ||||||
see DIV type 5 | ||||||
DKG | not reported | DEL Partial D | Eurasian D cluster | RHD(1155-412del1012) | 2017 | 2017 |
see weak D type 39 | ||||||
DNT | CDe | Partial D | Eurasian D cluster | RHD(N152T) | 2009 | 2013 |
see DYU | ||||||
see weak D type 37 | ||||||
see DBS-1 | ||||||
DUC-1 | not reported | D positive (apparently normal) | Eurasian D cluster | RHD(636C>T) | 2005 | 2005 |
see DV type 1 | ||||||
see DV type 2 | ||||||
see DV type 6 | ||||||
see DV type 1 | ||||||
see DBS-0 | ||||||
see DHK | ||||||
see DV type 4 | ||||||
see DV type 9 | ||||||
see DV type 8 | ||||||
see DV type 8 | ||||||
see DV type 4 | ||||||
see DV type 2 | ||||||
see DHK | ||||||
RHCE(5:697-5:744)-RHD | not reported | Partial D weakened D expression | Eurasian D cluster | RHD-RHCE(5:697-5:744)-RHD | 2018 | 2018 |
RHCE-D(3[361del11]-10) | not reported | D negative | Eurasian D cluster | RHD-RHCE(1-2)-RHD(361del11)(3-10) | ||
RHD delEx3 type 1 | not reported | Eurasian D cluster | RHD(335+649del10625) | 2017 | ||
RHD(-10C>T) | CDe | weakened D expression | Eurasian D cluster | RHD(-10C>T) | 2012 | |
RHD(-115A>C) | not reported | weakened D expression | Eurasian D cluster | RHD(-115A>C) | ||
RHD(1026C>T) | not reported | D negative | Eurasian D cluster | RHD(1026C>T) | 2015 | 2015 |
RHD(1026insAC) | not reported | Eurasian D cluster | RHD(1026insAC) | 2014 | ||
RHD(1056C>G) | not reported | weakened D expression | Eurasian D cluster | RHD(1056C>G) | 2017 | |
RHD(1065C>T) | CDe | weakened D expression | Eurasian D cluster | RHD(1065C>T) | 2014 | 2014 |
RHD(1067insA) | not reported | Eurasian D cluster | RHD(1067insA) | 2017 | ||
RHD(1166delA) | not reported | Eurasian D cluster | RHD(1166delA) | 2013 | ||
RHD(1209delT) | not reported | Eurasian D cluster | RHD(1209delT) | 2014 | ||
RHD(1269G>C) | CDe | weakened D expression | Eurasian D cluster | RHD(1269G>C) | 2011 | 2012 |
RHD(165C>T) | not reported | D positive (apparently normal) weakened D expression | Eurasian D cluster | RHD(165C>T) | ||
RHD(208delinsTG) | not reported | D negative | Eurasian D cluster | RHD(208delinsTG) | 2017 | |
RHD(255G>A, 1227G>A,) | not reported | Eurasian D cluster | RHD(255G>A, 1227G>A,) | 2017 | ||
RHD(26dupL) | not reported | weakened D expression | Eurasian D cluster | RHD(26insL) | 2011 | 2011 |
RHD(356de11) | not reported | Eurasian D cluster | RHD(356de11) | 2012 | ||
RHD(384T>C) | not reported | Eurasian D cluster | RHD(384T>C) | |||
RHD(396insGG) | not reported | Eurasian D cluster | RHD(396insGG) | 2016 | ||
RHD(510insG) | not reported | Eurasian D cluster | RHD(510insG) | 2015 | ||
RHD(519C>T) | CDe | weakened D expression | Eurasian D cluster | RHD(519C>T) | 2013 | |
RHD(520G>A,1080_1989del) | CDe | D negative | Eurasian D cluster | RHD(520G>A,1080_1989del) | 2014 | 2014 |
RHD(53dekT) | not reported | Eurasian D cluster | RHD(53dekT) | 2016 | ||
RHD(576C>T) | CDe | weakened D expression | Eurasian D cluster | RHD(576C>T) | 2011 | |
RHD(683del16) | not reported | Eurasian D cluster | RHD(683del16) | 2013 | ||
RHD(79delCTC) | not reported | Eurasian D cluster | RHD(79delCTC) | 2016 | ||
RHD(843G>T) | not reported | Eurasian D cluster | RHD(843G>T) | 2017 | ||
RHD(9393A>C) | not reported | Eurasian D cluster | RHD(IVS6+3A>C) | 2017 | ||
RHD(939G>C) | not reported | Eurasian D cluster | RHD(939G>C) | 2017 | ||
RHD(A137V,N152T)-CE(4-6)-D(7-10) | not reported | DIVa cluster | RHD(A137V,N152T)-CE(4-6)-D(7-10) | 2016 | ||
RHD(A176T) | not reported | Eurasian D cluster | RHD(A176T) | 2015 | 2015 | |
RHD(A209V) | not reported | D positive (no further data) | Eurasian D cluster | RHD(A209V) | 2011 | 2012 |
RHD(A237D) | not reported | Eurasian D cluster | RHD(A237D) | 2010 | ||
RHD(D350H) | not reported | Eurasian D cluster | RHD(D350H) | 2013 | ||
RHD(D35E,A399T) | not reported | weakened D expression | Eurasian D cluster | RHD(D35E,A399T) | 2016 | 2016 |
RHD(D40G) | not reported | Eurasian D cluster | RHD(D40G) | 2016 | ||
RHD(D95G) | not reported | weakened D expression | Eurasian D cluster | RHD(D95G) | 2007 | 2007 |
RHD(E340G) | not reported | Eurasian D cluster | RHD(E340G) | 2013 | ||
RHD(E369K) | not reported | Eurasian D cluster | RHD(E369K) | 2019 | ||
RHD(F161C) | CDe | weakened D expression | Eurasian D cluster | RHD(F161C) | 2015 | |
RHD(F179L) | CDe | D positive (no further data) | Eurasian D cluster | RHD(F179L) | 2012 | |
RHD(F179S) | not reported | Eurasian D cluster | RHD(F179S) | 2012 | ||
RHD(F223V,G278V) | not reported | D positive (no further data) | weak D type 4 cluster | RHD(F223V,G278V) | 2012 | 2012 |
RHD(F223V,K267M) | not reported | weak D type 4 cluster | RHD(F223V,K267M) | 2017 | ||
RHD(F31L) | CDe | DEL | Eurasian D cluster | RHD(F31L) | 2014 | 2014 |
RHD(G151D) | not reported | Eurasian D cluster | RHD(G151D) | 2017 | 2017 | |
RHD(G180R) | not reported | D positive (no further data) | Eurasian D cluster | RHD(G180R) | 2011 | 2012 |
RHD(G255R) | not reported | Eurasian D cluster | RHD(G255R) | 2012 | 2012 | |
RHD(G263L,T379M) | not reported | DAU cluster | RHD(G263L,T379M) | 2017 | ||
RHD(G263R,A399T) | not reported | Eurasian D cluster | RHD(G263R,A399T) | 2016 | ||
RHD(G307R) | not reported | Eurasian D cluster | RHD(G307R) | 2016 | ||
RHD(G308R) | not reported | Eurasian D cluster | RHD(G308R) | 2017 | ||
RHD(G353V) | not reported | Eurasian D cluster | RHD(G353V) | 2012 | 2012 | |
RHD(G353W,A354N) | not reported | D positive (no further data) | Eurasian D cluster | RHD-RHCE(7:1053-7:1061)-RHD | 2012 | 2012 |
RHD(G368R) | not reported | Eurasian D cluster | RHD(G368R) | 2014 | ||
RHD(G368W,D404E) | not reported | Eurasian D cluster | RHD(G368W,D404E) | 2015 | ||
RHD(G381R) | not reported | Eurasian D cluster | RHD(G381R) | 2017 | ||
RHD(G385V) | not reported | Eurasian D cluster | RHD(G385V) | 2016 | ||
RHD(G96R) | not reported | Eurasian D cluster | RHD(G96R) | 2016 | ||
RHD(G96S) | CDe | weakened D expression | Eurasian D cluster | RHD(G96S) | 2005 | |
RHD(H166D) | not reported | Eurasian D cluster | RHD(H166D) | 2016 | ||
RHD(H171D) | CDe | D positive (no further data) | Eurasian D cluster | RHD(H171D) | 2012 | |
RHD(H72P,S73C) | not reported | Eurasian D cluster | RHD(H72P,S73C) | 2016 | ||
RHD(I341N) | not reported | weakened D expression | Eurasian D cluster | RHD(I341N) | 2016 | |
RHD(I392T) | not reported | D positive (no further data) | Eurasian D cluster | RHD(I392T) | 2011 | 2012 |
RHD(I60L) | not reported | Eurasian D cluster | RHD(I60L) | 2016 | ||
RHD(I60L,S68N,K198N,F223V,G314V,I342T) | not reported | weak D type weakened D expression | weak D type 4 cluster | RHD(I60L,S68N,K198N,F223V,G314V,I342T) | 2010 | |
RHD(I60V,S103P,F161S,L214F) | not reported | Eurasian D cluster | RHD(I60V,S103P,F161S,L214F) | 2012 | ||
RHD(IVS3+5G>A) | not reported | weakened D expression | Eurasian D cluster | RHD(IVS3+5G>A) | 2007 | 2007 |
RHD(IVS4+1G>A) | not reported | Eurasian D cluster | RHD(IVS4+1G>A) | 2012 | ||
RHD(IVS4+2T>A) | not reported | Eurasian D cluster | RHD(IVS4+2T>A) | 2012 | ||
RHD(IVS5+2T>A) | not reported | Eurasian D cluster | RHD(IVS5+2T>A) | 2012 | ||
RHD(IVS5-41delCTCT) | not reported | Eurasian D cluster | RHD(IVS5-41delCTCT) | 2012 | ||
RHD(IVS6-4A>C) | not reported | weakened D expression | Eurasian D cluster | RHD(IVS6-4A>C) | 2012 | |
RHD(IVS7+1G>A) | not reported | Eurasian D cluster | RHD(IVS7+1G>A) | 2016 | ||
RHD(IVS8+6T>C) | cDE | weakened D expression | Eurasian D cluster | RHD(IVS8+6T>C) | 2012 | |
RHD(IVS9+5G>C) | not reported | weakened D expression | Eurasian D cluster | RHD(1227+5G>C) | 2019 | |
RHD(K133N) | not reported | weakened D expression | Eurasian D cluster | RHD(K133N) | 2014 | |
RHD(K189N,S257F) | not reported | Eurasian D cluster | RHD(K189N,S257F) | 2016 | ||
RHD(K235N) | not reported | Eurasian D cluster | RHD(K235N) | 2017 | ||
RHD(K267M) | not reported | Eurasian D cluster | RHD(K267M) | 2016 | ||
RHD(K394T) | not reported | weakened D expression | Eurasian D cluster | RHD(K394T) | 2019 | |
RHD(L110P)-CE(3-9)-D | CDe | Eurasian D cluster | RHD(L110P)-CE(3-9)-D | 2014 | 2014 | |
RHD(L20P) | not reported | Eurasian D cluster | RHD(L20P) | 2017 | ||
RHD(L214F)-CE(7)-D | not reported | weakened D expression Partial D | Eurasian D cluster | RHD(L214F)-CE(7)-D | 2018 | 2018 |
RHD(L228Q) | not reported | Eurasian D cluster | RHD(L228Q) | 2012 | 2012 | |
RHD(L258S) | not reported | Eurasian D cluster | RHD(L258S) | 2017 | ||
RHD(L297P) | not reported | Eurasian D cluster | RHD(L297P) | 2016 | ||
RHD(L370L) | CDe | weakened D expression | Eurasian D cluster | RHD(L370L) | 2009 | |
RHD(L378P) | not reported | Eurasian D cluster | RHD(L378P) | 2019 | ||
RHD(L386X) | not reported | D negative | Eurasian D cluster | RHD(L386X) | 2014 | 2014 |
RHD(L390L) | not reported | weakened D expression | Eurasian D cluster | RHD(L390L) | 2010 | 2011 |
RHD(M118K,V174M) | not reported | Partial D | Eurasian D cluster | RHD(M118K,V174M) | 2017 | 2017 |
RHD(M155V) | not reported | Eurasian D cluster | RHD(M155V) | 2017 | ||
RHD(M1T) | cDE | Eurasian D cluster | RHD(M1T) | 2015 | 2015 | |
RHD(M1_S2insV,T379M) | not reported | DAU cluster | RHD(M1_S2insV,T379M) | 2008 | ||
RHD(M218I, F223V, S225F,Y269X) | not reported | D negative | weak D type 4 cluster | RHD(609G>A,654G>C,667T>G,674C>T,807T>G) | 2009 | |
RHD(N135D) | not reported | Eurasian D cluster | RHD(N135D) | 2014 | ||
RHD(N240H) | not reported | Eurasian D cluster | RHD(N240H) | 2014 | ||
RHD(P221R) | not reported | Eurasian D cluster | RHD(P221R) | 2016 | ||
RHD(P231L) | not reported | Eurasian D cluster | RHD(P231L) | 2016 | ||
RHD(P261A) | not reported | weakened D expression | Eurasian D cluster | RHD(P261A) | 2017 | |
RHD(P313P) | not reported | Eurasian D cluster | RHD(P313P) | 2012 | 2012 | |
RHD(P313T) | CDe | weakened D expression | Eurasian D cluster | RHD(P313T) | 2015 | |
RHD(Q49R) | not reported | weakened D expression | Eurasian D cluster | RHD(Q49R) | 2003 | |
RHD(Q89R) | not reported | Eurasian D cluster | RHD(Q89R) | 2014 | ||
RHD(R10L) | not reported | Eurasian D cluster | RHD(R10L) | 2015 | ||
RHD(R114Q,A399T) | not reported | Eurasian D cluster | RHD(R114Q,A399T) | 2017 | ||
RHD(R71S) | not reported | D positive (no further data) | Eurasian D cluster | RHD(R71S) | 2011 | 2012 |
RHD(S112G) | not reported | weakened D expression | Eurasian D cluster | RHD(S112G) | 2009 | |
RHD(S230I) | not reported | Eurasian D cluster | RHD(S230I) | 2016 | ||
RHD(S230N) | not reported | Eurasian D cluster | RHD(S230N) | 2016 | ||
RHD(S254L,T379M) | not reported | DAU cluster | RHD(S254L,T379M) | 2017 | ||
RHD(S266G,V270G) | not reported | Eurasian D cluster | RHD(S266G,V270G) | 2016 | ||
RHD(T148R,T195M) | not reported | Eurasian D cluster | RHD(T148R,T195M) | 2017 | ||
RHD(T201R)-CE(5)-D(I342T) | not reported | weakened D expression Partial D | weak D type 4 cluster | RHD(T201R)-CE(5)-D(I342T) | 2018 | 2018 |
RHD(T201R,F223V,G307R) | not reported | D positive (no further data) | weak D type 4 cluster | RHD(T201R,F223V,G307R) | 2012 | 2012 |
RHD(T201R,F223V,K264N,A273A) | not reported | weak D type 4 cluster | RHD(T201R,F223V,K264N,A273A) | 2016 | ||
RHD(T201R,V270G) | not reported | Eurasian D cluster | RHD(T201R,V270G) | 2017 | ||
RHD(T32N) | not reported | weakened D expression | Eurasian D cluster | RHD(T32N) | 2013 | 2014 |
RHD(V147M,A399T) | not reported | Eurasian D cluster | RHD(V147M,A399T) | 2016 | ||
RHD(V174M,G307R) | not reported | Eurasian D cluster | RHD(V174M,G307R) | 2017 | ||
RHD(V174M,V306I) | cDe | Eurasian D cluster | RHD(V174M,V306I) | 2012 | ||
RHD(V238L,V270G) | not reported | D positive (no further data) | Eurasian D cluster | RHD(V238L,V270G) | 2012 | 2012 |
RHD(V245L,G263R,K267M) | not reported | Eurasian D cluster | RHD(V245L,G263R,K267M) | 2017 | ||
RHD(V247L) | not reported | Eurasian D cluster | RHD(V247L) | 2017 | ||
RHD(V281L) | not reported | Eurasian D cluster | RHD(V281L) | 2016 | ||
RHD(V306I,Y311C) | not reported | Eurasian D cluster | RHD(V306I,Y311C) | 2016 | ||
RHD(V319G) | not reported | Eurasian D cluster | RHD(V319G) | 2017 | ||
RHD(V352I) | not reported | Eurasian D cluster | RHD(V352I) | 2012 | 2012 | |
RHD(V50D) | not reported | Eurasian D cluster | RHD(V50D) | 2016 | ||
RHD(V56M,W90X) | CDe | D negative D negative | Eurasian D cluster | RHD(V56M,W90X) | 2008 | 2009 |
RHD(W185X) [c,555G>A] | not reported | D negative | Eurasian D cluster | RHD(W185X) [c,555G>A] | 2015 | 2015 |
RHD(X418S) | not reported | Eurasian D cluster | RHD(X418S) | 2014 | ||
RHD(Y243X) | not reported | Eurasian D cluster | RHD(Y243X) | 2017 | ||
RHD(Y311C) | not reported | Eurasian D cluster | RHD(Y311C) | 2014 | 2014 | |
RHD(Y34C) | not reported | weakened D expression | Eurasian D cluster | RHD(Y34C) | 2011 | 2012 |
RHD(Y48C) | not reported | weakened D expression | Eurasian D cluster | RHD(Y48C) | 2016 | 2016 |
RHD*5'UTR-115C | not reported | Eurasian D cluster | RHD(1-115A>C) | 2017 | ||
see Ccdes-1 | ||||||
see Ccdes-1 | ||||||
RHD-cE(5-6)-D | not reported | Eurasian D cluster | RHD-cE(5-6)-D | 2015 | ||
RHD-ceAG.05(2)-D | not reported | Eurasian D cluster | RHD-RHCE(2)-RHD(A85G) | 2017 | ||
RHD-RHCE(10) | CDe | DEL | Eurasian D cluster | RHD-RHCE(10) | 2009 | 2009 |
RHD-RHCE(2)-RHD(F355S) | not reported | Eurasian D cluster | RHD-RHCE(2)-RHD(F355S) | 2012 | 2012 | |
RHD-RHCE(2-10) | Cde | D negative | no RHD | RHD-RHCE(2-10) | 2004 | 2004 |
RHD-RHCE(2-5)-RHD | not reported | DEL | Eurasian D cluster | RHD-RHCE(2-5)-RHD | ||
see Ccdes-1 | ||||||
RHD-RHCE(5:733-5:787)-RHD | not reported | Eurasian D cluster | RHD-RHCE(5:733-5:787)-RHD | 2016 | ||
RHD-RHCE(8-9)-RHD | CDe | D negative | Eurasian D cluster | RHD-RHCE(8-9)-RHD | 1997 | 1997 |
RHD-RHcE[226P](5:676-5:733)-RHD | not reported | Eurasian D cluster | RHD-RHcE[226P](5:676-5:733)-RHD | 2016 | ||
RHD-RHCE[245V](5)-RHD | not reported | Eurasian D cluster | RHD-RHCE[245V](5)-RHD | 2017 | ||
RHDex10del type 1 | not reported | weakened D expression DEL | Eurasian D cluster | RHD(1227+2874_1254+1317del) | 2012 | 2012 |
RHDex10del type 2 | not reported | D negative | Eurasian D cluster | RHD(1227-2108_1254+2785del) | 2017 | 2017 |
RHDex1del type 1 | cDe | DEL | Eurasian D cluster | RHD(c.1-15144_148+3158del) | 2017 | 2017 |
RHDpsi-OT1 | cDe | weak D type 4 cluster | 2012 | |||
weak D type 132.0.1 | not reported | weak D type | Eurasian D cluster | RHD(G132R) | 2016 | |
weak D type 146 | not reported | weakened D expression weak D type | Eurasian D cluster | RHD(E146D) | 2011 | 2014 |
weak D type 147 | not reported | weakened D expression weak D type | Eurasian D cluster | RHD(E146K) | 2012 | 2014 |
weak D type 148 | not reported | weakened D expression weak D type | Eurasian D cluster | RHD(N224D) | 2013 | 2014 |
weak D type 149 | not reported | weakened D expression | Eurasian D cluster | RHD(H260R) | 2013 | 2014 |
weak D type 150 | CDe | weakened D expression weak D type | Eurasian D cluster | RHD(327_487-4164dup) | 2018 | 2018 |
weak D type 151 | not reported | weak D type | Eurasian D cluster | RHD(A59T) | 2018 | 2018 |
weak D type 152 | not reported | weak D type weakened D expression | Eurasian D cluster | RHD(G63C) | 2018 | 2018 |
weak D type 153 | not reported | weak D type weakened D expression | Eurasian D cluster | RHD(S122W) | 2011 | 2012 |
weak D type 154 | not reported | weakened D expression weak D type | Eurasian D cluster | RHD(L216F) | 2012 | |
weak D type 155 | not reported | weakened D expression weak D type | Eurasian D cluster | RHD(A237V) | 2016 | 2018 |
weak D type 156 | not reported | D positive (no further data) | Eurasian D cluster | RHD(H397R) | 2011 | 2012 |
weak D type 4.4 | not reported | weak D type | weak D type 4 cluster | RHD(K198N,T201R,F223V) | 2016 | |
weak D type 4.5 | not reported | weak D type | weak D type 4 cluster | RHD(T201R,F223V,G355S) | 2016 | |
weak RHD(960G>A) | CDe | weakened D expression | Eurasian D cluster | RHD(960G>A) | 2007 | 2015 |
weak RHD(IVS3+3G>C) | cDE | weakened D expression | Eurasian D cluster | RHD(IVS3+3G>C) | 2008 | 2013 |
weak RHD(IVS4+5G>A) | CDe | weakened D expression | Eurasian D cluster | RHD(IVS4+5G>A) | 2009 | 2013 |
weak RHD(IVS6-14delTAA) | not reported | weakened D expression | Eurasian D cluster | RHD(IVS6-14delTAA) | 2008 | 2013 |