weak D type 149



Key changes from standard allele

779A>G (H260R)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.779 A>G

Amino acid changes relative to standard protein

His to Arg at codon 260


ISBT group

Phenotype characterization and grouping

weakened D expression

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster


First submission to GenBank: 2013 KF142383 (submitted 2013-05-22, released 2013-09-18)

First full publication: 2014 He J et. al. Transfusion. 2015 Jan;55(1):137-43. doi: 10.1111/trf.12797. Epub 2014 Jul 29.

Other relevant descriptions:
KP718117 (submitted 2015-01-28, released 2015-07-25)
KJ486497 (submitted 2014-02-21, released 2014-05-05)


weak D KF142383
weak D variant KP718117
weak D phenotype Colin Y et. al. Blood. 1991 Nov 15;78(10):2747-52.


China (general): KF142383
China (general): KP718117

Additional comments

Last update: 2018-05-23 (yyyy-MM-dd)