Designation | ISBT name | Cluster | Phenotype | Mechanism | Alterations | First mention | Definitive publication |
D-SPM | RHD*40 RHD*D-SPM | DIVa cluster | Partial D | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V) | 2012 | |
DAR1 (weak D type 4.2.0) | RHD*09.01.00 RHD*DAR1.00 | weak D type 4 cluster | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) | 1998 | 1999 |
DAR(CE2:V50V-S68N) | RHD*09.06 RHD*DAR6 RHD*DAR(SE2:v50V-S68N) | weak D type 4 cluster | Partial D | Complex changes | 1025T>C (I342T) 150T>C 178A>C (I60L) 201G>A 203G>A (S68N) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2013 | |
DAR(T203A) | RHD*09.01 RHD*DAR | weak D type 4 cluster | Partial D | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 607A>G (T203A) 667T>G (F223V) 744C>T 957 G>A | 2012 | 2012 |
DAR-E | RHD*09.02 RHD*DAR2 | weak D type 4 cluster | Partial D weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 957 G>A | 2006 | 2006 |
DAU-13 | RHD*10.13 RHD*DAU13 | DAU cluster | Multiple missense mutations | 1136C>T (T379M) 48G>C (W16C) | 2013 | ||
DAU-0 | RHD*10.00 RHD*DAU0 | DAU cluster | D positive (apparently normal) Partial D | Single missense mutation | 1136C>T (T379M) | 2002 | 2002 |
DAU-0.1 | RHD*10.00.01 RHD*DAU0.01 | DAU cluster | Multiple missense mutations | 1136C>T (T379M) 579G>A | 2003 | 2003 | |
DAU-1 | RHD*10.01 RHD*DAU1 | DAU cluster | Partial D | Multiple missense mutations | 1136C>T (T379M) 689G>T (S230I) | 2002 | 2002 |
DAU-2 | RHD*10.02 RHD*DAU2 | DAU cluster | Partial D weakened D expression | Multiple missense mutations | 1136C>T (T379M) 209G>A (R70Q) 998G>A (S333N) | 2002 | 2002 |
DAU-3 | RHD*10.03 RHD*DAU3 | DAU cluster | Partial D | Multiple missense mutations | 1136C>T (T379M) 835G>A (V279M) | 2002 | 2002 |
DAU-4 | RHD*10.04 RHD*DAU4 | DAU cluster | Partial D weakened D expression | Multiple missense mutations | 1136C>T (T379M) 697G>A (E233K) | 2002 | 2002 |
DAU-5 | RHD*10.05 RHD*DAU5 | DAU cluster | Partial D | Multiple missense mutations | 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q) | 2005 | 2005 |
DAU-6 | RHD*10.06 RHD*DAU6 | DAU cluster | Partial D | Multiple missense mutations | 1136C>T (T379M) 998G>A (S333N) | 2005 | 2005 |
DAU-7 | RHD*10.07 RHD*DAU7 | DAU cluster | Partial D | Single missense mutation | 1136C>T (T379M) 835G>A (V279M) 998G>A (S333N) | 2009 | 2009 |
DFV.1 | weak D type 4 cluster | weakened D expression | Single missense mutation | 667T>G (F223V) 819G>A | 2013 | 2014 | |
DIII type 5 | RHD*03.01 RHD*DIIIa | DIVa cluster | Partial D D category | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | ||
DIII type 6 | RHD*03.06 RHD*DIII.6 | DIVa cluster | Partial D D category | Multiple missense mutations | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2005 | 2006 |
DIII type 7 | RHD*03.07 RHD*DIII.07 | DIVa cluster | Partial D D category | Complex changes | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A Hybrid RHCE(2) | 2005 | 2006 |
DIV(S103P) | DIVa cluster | Multiple missense mutations | 186G>T (L62F) 307T>C (S103P) 410C>T (A137V) 455A>C (N152T) | 2013 | |||
DIV type 1.0 | RHD*04.01 RHD*DIVa. | DIVa cluster | Partial D D category | Multiple missense mutations | 1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2012 | |
DMA | RHD*35 RHD*DMA | Eurasian D cluster | Single missense mutation | 621G>C (L207F) | 2003 | 2003 | |
DMH | RHD*23 RHD*DMH | Eurasian D cluster | Partial D | Missense (splice site affected) | 161T>C (L54P) | 1999 | |
DOL-1 | RHD*12.01 RHD*DOL1 | weak D type 4 cluster | Partial D | Multiple missense mutations | 509T>C (M170T) 667T>G (F223V) | 1999 | 2009 |
DWN | RHD*49 RHD*DWN | Eurasian D cluster | Partial D | hybrid allele | Hybrid RHCE(7:1053-7:1061) | 2013 | 2013 |
DYU | RHD*29 RHD*DYU | Eurasian D cluster | Partial D | Single missense mutation | 700A>T (R234W) | 2003 | 2005 |
RHD psi | RHD*08N.01 RHD*Pseudogene | weak D type 4 cluster | D negative | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 807T>G (Y269X) IVS3-19 dupl 37 | 2000 | 2000 |
RHD(1347A>G) | Eurasian D cluster | untranslated region | 1347A>G | 2003 | 2003 | ||
RHD(545delCTGT) | RHD*01N.46 | Eurasian D cluster | D negative | Short deletion | 545delCTGT | 2012 | 2012 |
weak D type 96 | RHD* 01W.96 RHD*weak D type 96 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 731C>T (A244V) | 2013 | 2013 |
DAU-11 | RHD*10.11 RHD*DAU11 | DAU cluster | weakened D expression | Multiple missense mutations | 1136C>T (T379M) 254C>T (A85V) 835G>A (V279M) | 2012 | 2016 |
weak D type 141 | RHD*52 RHD* 01W.141 | Eurasian D cluster | Partial D weakened D expression weak D type | Single missense mutation | 668T>C (F223S) | 2015 | 2016 |
DAU-5.1 | RHD*10.05.01 RHD*DAU5.01 | DAU cluster | weakened D expression | Multiple missense mutations | 1122C>T (I374I) 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q) | 2014 | 2016 |
RHD(G212R) | RHD*01EL.16 RHD*DEL16 | Eurasian D cluster | DEL | Missense (splice site affected) | 634G>C (G212R) | 2008 | 2009 |
DAU-12 | RHD*10.12 RHD*DAU12 | DAU cluster | Multiple missense mutations | 1136C>T (T379M) 542T>C (L181P) | 2012 | ||
DAU-14 | RHD*10.14 RHD*DAU14 | DAU cluster | D positive (no further data) | Multiple missense mutations | 1136C>T (T379M) 201G>A 203G>A (S68N) | 2014 | 2014 |
RHD(V174M,V306I) | Eurasian D cluster | Multiple missense mutations | 520G>A (V174M) 916G>A (V306I) | 2012 | |||
RHDex1del type 1 | Eurasian D cluster | DEL | large deletion | del25257404_25275848 | 2017 | 2017 | |
RHDpsi-OT1 | weak D type 4 cluster | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 835G>A (V279M) IVS3-19 dupl 37 IVS7-214ins ACAG | 2012 | |||
weak D type 11 | RHD*11 RHD*weak partial 11 | Eurasian D cluster | weak D type weakened D expression Partial D | Single missense mutation | 885G>T (M295I) | 1999 | 1999 |
weak D type 19 | RHD*01W.19 RHD*weak D type 19 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 611T>C (I204T) | 2006 | 2006 |
weak D type 29 | RHD*01W.29 RHD*weak D type 29 | weak D type 4 cluster | weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 178A>C (I60L) 201G>A 203G>A (S68N) 594A>T (K198N) 667T>G (F223V) 744C>T 957 G>A | 2003 | 2003 |
weak D type 4.0 | RHD*09.03.01 RHD*DAR3 | weak D type 4 cluster | weak D type weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A | 1999 | 1999 |
weak D type 4.0.1 | RHD*09.03 RHD*DAR3 | weak D type 4 cluster | weak D type weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) | ||
weak D type 4.1 | RHD*09.04 RHD*DAR4 | weak D type 4 cluster | weak D type weakened D expression | Multiple missense mutations | 48G>C (W16C) 602C>G (T201R) 667T>G (F223V) 819G>A | 2000 | 2000 |
weak D type 4.2.1 (DAR1.1) | RHD*09.01.01 RHD*DAR1.01 RHD*weak 4.2 | weak D type 4 cluster | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2000 | 2000 |
weak D type 4.2.2 (DAR1.2) | RHD*09.01.02 | weak D type 4 cluster | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T 957 G>A | 2000 | 2000 |
weak D type 4.2.3 (DAR1.3) | RHD*09.01.03 RHD*DAR1.03 | weak D type 4 cluster | weak D type Partial D weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T | 2008 | |
weak D type 4.3 | RHD*09. 05 RHD*weak 4.3 | weak D type 4 cluster | weak D type DEL weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A 872C>G (P291R) | 2004 | |
weak D type 65 | RHD*01W.65 RHD*weak D type 65 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 68C>A (A23D) | 2008 |