Complex changes

DesignationISBT nameHaplotypePhenotypeClusterAlterationsFirst mentionDefinitive publication
Ccdes-1RHD*03N.01
CcdeD negativeDIVa cluster1006G>T (G336C)
186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
Hybrid RHCE[245V](4-7)
20042004
DAR(CE2:V50V-S68N)RHD*09.06
RHD*DAR6
RHD*DAR(SE2:v50V-S68N)
cDePartial Dweak D type 4 cluster1025T>C (I342T)
150T>C
178A>C (I60L)
201G>A
203G>A (S68N)
602C>G (T201R)
667T>G (F223V)
957 G>A
2013
DFR-3RHD*17.03
RHD*DFR3
CDePartial DEurasian D cluster539G>C (G180A)
Hybrid RHCE(4:505-4:514)
20072007
DIII type 7RHD*03.07
RHD*DIII.07
cDePartial D
D category
DIVa cluster410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
Hybrid RHCE(2)
20052006
DLXRHD*46
RHD*DLX
cDEPartial DEurasian D cluster667T>G (F223V)
Hybrid RHCE(5:712-6)
20122012
RHD psiRHD*08N.01
RHD*Pseudogene
cDeD negativeweak D type 4 cluster609G>A
654G>C (M218I)
667T>G (F223V)
674C>T (S225F)
807T>G (Y269X)
IVS3-19 dupl 37
20002000
DAU-0.2RHD*10.00.02
RHD*DAU0.02
not reportedEurasian D cluster1136C>T (T379M)
150T>C
RHD(216dupCA,1195G>A)RHD*01N.45CDeD negativeEurasian D cluster1195G>A (A399T)
216dupCA
2012
RHD(909ins TGGCT, IVS6+2del TAAG)RHD*01N.27CDeD negativeEurasian D cluster909ins TGGCT
IVS6+2del TAAG
20022002
weak D type 41.0.1RHD*01w.41.0.1
RHD*weak D type 41.01.
not reportedweak D type
weakened D expression
Eurasian D cluster1170T>C (L390L)
1193A>T (E398V)
2016
RHD(M1V,T379M)RHD*10.15
RHD*DAU15
not reportedDAU cluster1136C>T (T379M)
1A>G (M1V)
2008
RHD(M218I, F223V, S225F,Y269X)not reportedD negativeweak D type 4 cluster609G>A
654G>C (M218I)
667T>G (F223V)
674C>T (S225F)
807T>G (Y269X)
2009
RHDpsi-OT1cDeweak D type 4 cluster609G>A
654G>C (M218I)
667T>G (F223V)
674C>T (S225F)
835G>A (V279M)
IVS3-19 dupl 37
IVS7-214ins ACAG
2012