Designation | ISBT name | Cluster | Haplotype | Mechanism | Alterations | First mention | Definitive publication |
DII | RHD*02 RHD*DII | Eurasian D cluster | CDe | Single missense mutation | 1061C>A (A354D) | 1997 | 1997 |
DIII type 4 | RHD*03.04 RHD*DIII.4 | DIVa cluster | CDe | hybrid allele | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2000 | 2000 |
DIII type 5 | RHD*03.01 RHD*DIIIa | DIVa cluster | cDe | Multiple missense mutations | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | ||
DIII type 6 | RHD*03.06 RHD*DIII.6 | DIVa cluster | cDe | Multiple missense mutations | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2005 | 2006 |
DIII type 7 | RHD*03.07 RHD*DIII.07 | DIVa cluster | cDe | Complex changes | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A Hybrid RHCE(2) | 2005 | 2006 |
DIII type 8 | RHD*03.08 RHD*DIII.08 | DIVa cluster | not reported | Multiple missense mutations | 410C>T (A137V) 455A>C (N152T) | 2010 | |
DIIIc | RHD*03.03 RHD*DIIIc | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3) | 1996 | 1996 |
DIV type 1.0 | RHD*04.01 RHD*DIVa. | DIVa cluster | cDe | Multiple missense mutations | 1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2012 | |
DIV type 3 | RHD*04.03 RHD* DIV.3 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(6-9) | 1999 | 1999 |
DIV type 4 | RHD*04.04 RHD*DIV.4 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(7:1048-7:1061) | 1998 | |
DIV type 5 | RHD*04.05 RHD*DIV.5 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHCE(7-9) | 2000 | 2000 |
DV type 1 | RHD*05.01 RHD*DV.1 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:697) | 1995 | 1995 |
DV type 2 | RHD*05.02 RHD*DV.2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5) | 1995 | 1995 |
DV type 4 | RHD*05.04 RHD*DV.4 | Eurasian D cluster | CDe | Single missense mutation | 697G>C (E233Q) | 1998 | 1999 |
DV type 6 | RHD*05.06 RHD*DV.6 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:712) | 1998 | 1999 |
DV type 7 | RHD*05.07 RHD*DV.7 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:787) | 2001 | 2001 |
DV type 8 | RHD*05.08 RHD*DV.8 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:667-5:744) | 1998 | 1999 |
DV type 9 | RHD*05.09 RHD*DV.9 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(5:697-5:712) | 1999 | 2000 |
DVI type 1 | RHD*06.01 RHD*DVI.1 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](4-5) | 1997 | 1997 |
DVI type 2 | RHD*06.02 RHD*DVI.2 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(4-6) | 1994 | 1994 |
DVI type 3 | RHD*06.03 RHD*DVI.3 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3-6) | 1998 | 1998 |
DVI type 4 | RHD*06.04 RHD*DVI.4 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(3-5) | 2000 | 2006 |
DVII | RHD*07.01 RHD*DVII.1 | Eurasian D cluster | CDe | Single missense mutation | 329T>C (L110P) | 1995 | 1995 |
RHD-RHCE(7)-RHD | RHD*58 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHCE(7) | 2012 |