D category

DesignationISBT nameClusterHaplotypeMechanismAlterationsFirst mentionDefinitive publication
DIIRHD*02
RHD*DII
Eurasian D clusterCDeSingle missense mutation1061C>A (A354D)
19971997
DIII type 4RHD*03.04
RHD*DIII.4
DIVa clusterCDehybrid allele186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
20002000
DIII type 5RHD*03.01
RHD*DIIIa
DIVa clustercDeMultiple missense mutations186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
DIII type 6RHD*03.06
RHD*DIII.6
DIVa clustercDeMultiple missense mutations410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
20052006
DIII type 7RHD*03.07
RHD*DIII.07
DIVa clustercDeComplex changes410C>T (A137V)
455A>C (N152T)
602C>G (T201R)
667T>G (F223V)
819G>A
Hybrid RHCE(2)
20052006
DIII type 8RHD*03.08
RHD*DIII.08
DIVa clusternot reportedMultiple missense mutations410C>T (A137V)
455A>C (N152T)
2010
DIIIcRHD*03.03
RHD*DIIIc
Eurasian D clusterCDehybrid alleleHybrid RHCE(3)
19961996
DIV type 1.0RHD*04.01
RHD*DIVa.
DIVa clustercDeMultiple missense mutations1048G>C (D350H)
186G>T (L62F)
410C>T (A137V)
455A>C (N152T)
2012
DIV type 3RHD*04.03
RHD* DIV.3
Eurasian D clusterCDehybrid alleleHybrid RHCE(6-9)
19991999
DIV type 4RHD*04.04
RHD*DIV.4
Eurasian D clusterCDehybrid alleleHybrid RHCE(7:1048-7:1061)
1998
DIV type 5RHD*04.05
RHD*DIV.5
Eurasian D clustercDEhybrid alleleHybrid RHCE(7-9)
20002000
DV type 1RHD*05.01
RHD*DV.1
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:697)
19951995
DV type 2RHD*05.02
RHD*DV.2
Eurasian D clusterCDehybrid alleleHybrid RHCE(5)
19951995
DV type 4RHD*05.04
RHD*DV.4
Eurasian D clusterCDeSingle missense mutation697G>C (E233Q)
19981999
DV type 6RHD*05.06
RHD*DV.6
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:712)
19981999
DV type 7RHD*05.07
RHD*DV.7
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:787)
20012001
DV type 8RHD*05.08
RHD*DV.8
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:667-5:744)
19981999
DV type 9RHD*05.09
RHD*DV.9
Eurasian D clusterCDehybrid alleleHybrid RHCE(5:697-5:712)
19992000
DVI type 1RHD*06.01
RHD*DVI.1
Eurasian D clustercDEhybrid alleleHybrid RHcE[226P](4-5)
19971997
DVI type 2RHD*06.02
RHD*DVI.2
Eurasian D clusterCDehybrid alleleHybrid RHCE(4-6)
19941994
DVI type 3RHD*06.03
RHD*DVI.3
Eurasian D clusterCDehybrid alleleHybrid RHCE(3-6)
19981998
DVI type 4RHD*06.04
RHD*DVI.4
Eurasian D clusterCDehybrid alleleHybrid RHCE(3-5)
20002006
DVIIRHD*07.01
RHD*DVII.1
Eurasian D clusterCDeSingle missense mutation329T>C (L110P)
19951995
RHD-RHCE(7)-RHDRHD*58Eurasian D clustercDEhybrid alleleHybrid RHCE(7)
2012