Designation | ISBT name | Haplotype | Phenotype | Cluster | Alterations | First mention | Definitive publication |
D-SPM | RHD*40 RHD*D-SPM | cDe | Partial D | DIVa cluster | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 509T>C (M170T) 667T>G (F223V) | 2012 | |
DAR1 (weak D type 4.2.0) | RHD*09.01.00 RHD*DAR1.00 | cDe | Partial D weak D type weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) | 1998 | 1999 |
DAR(T203A) | RHD*09.01 RHD*DAR | cDe | Partial D | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 607A>G (T203A) 667T>G (F223V) 744C>T 957 G>A | 2012 | 2012 |
DAR-E | RHD*09.02 RHD*DAR2 | cDe | Partial D weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 957 G>A | 2006 | 2006 |
DAR2.1 | RHD*09.02.01 RHD*DAR2.01 | not reported | Partial D | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 744C>T 957 G>A | ||
DAU-13 | RHD*10.13 RHD*DAU13 | cDe | DAU cluster | 1136C>T (T379M) 48G>C (W16C) | 2013 | ||
DAU-0.1 | RHD*10.00.01 RHD*DAU0.01 | cDe | DAU cluster | 1136C>T (T379M) 579G>A | 2003 | 2003 | |
DAU-1 | RHD*10.01 RHD*DAU1 | cDe | Partial D | DAU cluster | 1136C>T (T379M) 689G>T (S230I) | 2002 | 2002 |
DAU-2 | RHD*10.02 RHD*DAU2 | cDe | Partial D weakened D expression | DAU cluster | 1136C>T (T379M) 209G>A (R70Q) 998G>A (S333N) | 2002 | 2002 |
DAU-3 | RHD*10.03 RHD*DAU3 | cDe | Partial D | DAU cluster | 1136C>T (T379M) 835G>A (V279M) | 2002 | 2002 |
DAU-4 | RHD*10.04 RHD*DAU4 | cDe | Partial D weakened D expression | DAU cluster | 1136C>T (T379M) 697G>A (E233K) | 2002 | 2002 |
DAU-5 | RHD*10.05 RHD*DAU5 | cDe | Partial D | DAU cluster | 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q) | 2005 | 2005 |
DAU-6 | RHD*10.06 RHD*DAU6 | cDe | Partial D | DAU cluster | 1136C>T (T379M) 998G>A (S333N) | 2005 | 2005 |
DIII type 5 | RHD*03.01 RHD*DIIIa | cDe | Partial D D category | DIVa cluster | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | ||
DIII type 6 | RHD*03.06 RHD*DIII.6 | cDe | Partial D D category | DIVa cluster | 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2005 | 2006 |
DIII type 8 | RHD*03.08 RHD*DIII.08 | not reported | Partial D D category | DIVa cluster | 410C>T (A137V) 455A>C (N152T) | 2010 | |
DIII type 9 | RHD*03.09 RHD*DIII.09 | not reported | Partial D | DIVa cluster | 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 667T>G (F223V) | ||
DIIIa150C | not reported | DIVa cluster | 150T>C 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2012 | |||
DIV(S103P) | cDe | DIVa cluster | 186G>T (L62F) 307T>C (S103P) 410C>T (A137V) 455A>C (N152T) | 2013 | |||
DIV type 1.1 (obsolete) | cDe | Partial D D category | DIVa cluster | 1048G>C (D350H) 186G>T (L62F) 455A>C (N152T) | 1995 | 1995 | |
DIV type 1.0 | RHD*04.01 RHD*DIVa. | cDe | Partial D D category | DIVa cluster | 1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) | 2012 | |
DOL-1 | RHD*12.01 RHD*DOL1 | cDe | Partial D | weak D type 4 cluster | 509T>C (M170T) 667T>G (F223V) | 1999 | 2009 |
DOL-2 | RHD*12.02 RHD*DOL2 | not reported | Partial D | weak D type 4 cluster | 1132C>G (L378V) 509T>C (M170T) 667T>G (F223V) | 2005 | 2009 |
DOL-3 | RHD*12.03 RHD*DOL3 | not reported | Partial D | weak D type 4 cluster | 410C>T (A137V) 509T>C (M170T) 667T>G (F223V) | 2005 | |
DTO | RHD*30 RHD*DTO | not reported | weakened D expression Partial D | weak D type 4 cluster | 667T>G (F223V) 674C>T (S225F) | 2005 | 2005 |
DVII type 2 | RHD*07.02 RHD*DVII.2 | CDe | Partial D | Eurasian D cluster | 307T>C (S103P) 329T>C (L110P) | 2001 | 2001 |
weak D type 89 | RHD* 01W.89 RHD*weak D type 89 | CDe | weak D type weakened D expression | Eurasian D cluster | 67G>C (A23P) | 2014 | 2014 |
DAU-11 | RHD*10.11 RHD*DAU11 | cDe | weakened D expression | DAU cluster | 1136C>T (T379M) 254C>T (A85V) 835G>A (V279M) | 2012 | 2016 |
RHD(D35E,A399T) | not reported | weakened D expression | Eurasian D cluster | 105C>G (D35E) 1195G>A (A399T) | 2016 | 2016 | |
DAU-9 | RHD*10.09 RHD*DAU9 | not reported | D positive (no further data) | DAU cluster | 1136C>T (T379M) 535T>C (F179L) | 2012 | 2012 |
DAU-5.1 | RHD*10.05.01 RHD*DAU5.01 | cDe | weakened D expression | DAU cluster | 1122C>T (I374I) 1136C>T (T379M) 667T>G (F223V) 697G>C (E233Q) | 2014 | 2016 |
RHD(F223V,G278V) | not reported | D positive (no further data) | weak D type 4 cluster | 667T>G (F223V) 833G>T (G278V) | 2012 | 2012 | |
RHD(F223V,K267M) | not reported | weak D type 4 cluster | 667T>G (F223V) 800A>T (K267M) | 2017 | |||
RHD(G263L,T379M) | not reported | DAU cluster | 1136C>T (T379M) 787GG>TT (G263L) | 2017 | |||
RHD(G263R,A399T) | not reported | Eurasian D cluster | 1195G>A (A399T) 787G>A (G263R) | 2016 | |||
RHD(G368W,D404E) | not reported | Eurasian D cluster | 1102G>T (G368W) 1212C>A (D404E) | 2015 | |||
RHD(H72P,S73C) | not reported | Eurasian D cluster | 215AC>CA (72H>P) 217A>T (S73C) | 2016 | |||
RHD(I60L,N152T,T201R,F223V,G263R) (obsolete) | cDe | Partial D | DIVa cluster | 1170T>C 178A>C (I60L) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 744C>T 787G>A (G263R) | 1999 | ||
RHD(I60V,S103P,F161S,L214F) | not reported | Eurasian D cluster | 178A>G (I60V) 307T>C (S103P) 482T>C (F161S) 640C>T (L214F) 966T>C | 2012 | |||
RHD(K189N,S257F) | not reported | Eurasian D cluster | 567G>T (K189N) 770C>T (S257F) | 2016 | |||
weak D type 4.4 | not reported | weak D type | weak D type 4 cluster | 594A>T (K198N) 602C>G (T201R) 667T>G (F223V) 819G>A | 2016 | ||
DAU-12 | RHD*10.12 RHD*DAU12 | cDe | DAU cluster | 1136C>T (T379M) 542T>C (L181P) | 2012 | ||
weak D type 10.1 | RHD*01W.10.1 RHD*weak D type 10.1 | not reported | weak D type weakened D expression | Eurasian D cluster | 1145T>C (L382P) 1177T>C (W393R) | 2016 | |
weak D type 41.0.1 | RHD*01w.41.0.1 RHD*weak D type 41.01. | not reported | weak D type weakened D expression | Eurasian D cluster | 1170T>C (L390L) 1193A>T (E398V) | 2016 | |
RHD(M118K,V174M) | not reported | Partial D | Eurasian D cluster | 353T>A (M118K) 520G>A (V174M) | 2017 | 2017 | |
RHD(M218I, F223V, S225F) (obsolete) | CDe | weakened D expression | weak D type 4 cluster | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) IVS3-19 dupl 37 | 2013 | ||
RHD(N152T,T201R,F223V) (obsolete) | cDe | Partial D | DIVa cluster | 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) | 1997 | 1997 | |
RHD(N152T,V270G) | RHD*62 | not reported | Eurasian D cluster | 455A>C (N152T) 809T>G (V270G) | 2014 | ||
DAU-8 | RHD*10.08 RHD*DAU8 | not reported | D positive (no further data) | DAU cluster | 1136C>T (T379M) 340C>T (R114W) 579G>A | 2012 | 2012 |
weak D type 45.2 | RHD*01w.45.2 RHDÜweak D type 45.2 | CDe | weak D type weakened D expression | Eurasian D cluster | 1195G>A (A399T) 208C>T (R70W) 818C>T (A273V) | 2013 | 2013 |
RHD(S254L,T379M) | not reported | DAU cluster | 1136C>T (T379M) 761C>T (S254L) | 2017 | |||
weak D type 3.1 | RHD*01W.3.1 RHD*weak D type 3.1 | CDe | weak D type weakened D expression | Eurasian D cluster | 178A>C (I60L) 8C>G (S3C) | 2014 | 2014 |
DAU-14 | RHD*10.14 RHD*DAU14 | cDe | D positive (no further data) | DAU cluster | 1136C>T (T379M) 201G>A 203G>A (S68N) | 2014 | 2014 |
RHD(T148R,T195M) | not reported | Eurasian D cluster | 443C>G (T148R) 584C>T (T195M) | 2017 | |||
RHD(T201R,F223V,G307R) | not reported | D positive (no further data) | weak D type 4 cluster | 602C>G (T201R) 667T>G (F223V) 819G>A 919G>A (G307R) | 2012 | 2012 | |
weak D type 4.5 | not reported | weak D type | weak D type 4 cluster | 1063G>A (G355S) 602C>G (T201R) 667T>G (F223V) 819G>A | 2016 | ||
RHD(T201R,F223V,K264N,A273A) | not reported | weak D type 4 cluster | 602C>G (T201R) 667T>G (F223V) 792G>T (K264N) 819G>A | 2016 | |||
RHD(T201R,V270G) | not reported | Eurasian D cluster | 602C>G (T201R) 809T>G (V270G) | 2017 | |||
RHD(V147M,A399T) | not reported | Eurasian D cluster | 1195G>A (A399T) 1195G>A (V147M) | 2016 | |||
RHD(V174M,G307R) | not reported | Eurasian D cluster | 520G>A (V174M) 919G>A (G307R) | 2017 | |||
RHD(V174M,V306I) | cDe | Eurasian D cluster | 520G>A (V174M) 916G>A (V306I) | 2012 | |||
RHD(V238L,V270G) | not reported | D positive (no further data) | Eurasian D cluster | 712G>C (V238L) 809T>G (V270G) | 2012 | 2012 | |
weak D type 1.2 | RHD*01w.1.2 RHD*weak D type 1.2 | CDe | weak D type weakened D expression | Eurasian D cluster | 712G>A (V238M) 809T>G (V270G) | 2014 | 2014 |
RHD(V245L,G263R,K267M) | not reported | Eurasian D cluster | 733G>C (V245L) 744C>T 787G>A (G263R) 800A>T (K267M) | 2017 | |||
DAU-10 | RHD*10.10 RHD*DAU10 | not reported | D positive (no further data) | DAU cluster | 1136C>T (T379M) 579G>A 739G>C (V247L) | 2012 | 2012 |
weak D type 2.2 | RHD*01W.2.2 RHD*weak D type 2.2 | cDE | weak D type weakened D expression | Eurasian D cluster | 1154G>C (G385A) 916G>A (V306I) 932A>G (Y311C) | 2014 | 2014 |
weak D type 10.2 | RHD*01W.10.2 RHD*weak D type 10.2 | not reported | weakened D expression weak D type | Eurasian D cluster | 1177T>C (W393R) 1199A>C (K400T) | 2015 | 2016 |
weak D type 1.1 | RHD*01W.1.1 RHD*weak D type 1.1 | CDe | weak D type weakened D expression | Eurasian D cluster | 52C>G (L18V) 809T>G (V270G) | 2004 | 2005 |
weak D type 14 | RHD*01W.14 RHD*weak D type 14 | cDE | weak D type weakened D expression | Eurasian D cluster | 544T>A (S182T) 594A>T (K198N) 602C>G (T201R) | 1999 | 1999 |
weak D type 2.1 | RHD*01W.2.1 RHD*weak D type 2.1 | cDE | weak D type weakened D expression | Eurasian D cluster | 1154G>C (G385A) 301T>A (F101I) | 2009 | |
weak D type 29 | RHD*01W.29 RHD*weak D type 29 | cDe | weak D type weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 178A>C (I60L) 201G>A 203G>A (S68N) 594A>T (K198N) 667T>G (F223V) 744C>T 957 G>A | 2003 | 2003 |
RHD(I60L,S68N,K198N,F223V,G314V,I342T) | not reported | weak D type weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 178A>C (I60L) 201G>A 203G>A (S68N) 594A>T (K198N) 667T>G (F223V) 744C>T 941G>T (G314V) | 2010 | ||
weak D type 30 | RHD*01W.30 RHD*weak D type 30 | not reported | weak D type weakened D expression | Eurasian D cluster | 1018GA>AT (E340M) | 2003 | |
weak D type 4.0 | RHD*09.03.01 RHD*DAR3 | cDe | weak D type weakened D expression Partial D | weak D type 4 cluster | 602C>G (T201R) 667T>G (F223V) 819G>A | 1999 | 1999 |
weak D type 4.0.1 | RHD*09.03 RHD*DAR3 | cDe | weak D type weakened D expression Partial D | weak D type 4 cluster | 602C>G (T201R) 667T>G (F223V) | ||
weak D type 4.1 | RHD*09.04 RHD*DAR4 | cDe | weak D type weakened D expression | weak D type 4 cluster | 48G>C (W16C) 602C>G (T201R) 667T>G (F223V) 819G>A | 2000 | 2000 |
weak D type 4.2.1 (DAR1.1) | RHD*09.01.01 RHD*DAR1.01 RHD*weak 4.2 | cDe | Partial D weak D type weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2000 | 2000 |
weak D type 4.2.2 (DAR1.2) | RHD*09.01.02 | cDe | Partial D weak D type weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T 957 G>A | 2000 | 2000 |
weak D type 4.2.3 (DAR1.3) | RHD*09.01.03 RHD*DAR1.03 | cDe | weak D type Partial D weakened D expression | weak D type 4 cluster | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T | 2008 | |
weak D type 4.3 | RHD*09. 05 RHD*weak 4.3 | cDe | weak D type DEL weakened D expression Partial D | weak D type 4 cluster | 602C>G (T201R) 667T>G (F223V) 819G>A 872C>G (P291R) | 2004 | |
weak D type 45.1 | RHD*01w.45.1 RHDÜweak D type 45.1 | not reported | weak D type weakened D expression | Eurasian D cluster | 1195G>A (A399T) 818C>T (A273V) | 2010 | |
weak D type 68 | RHD*01W.68 RHD*weak D type 68 | not reported | weak D type weakened D expression | Eurasian D cluster | 1213C>G (Q405E) 165C>T | 2006 |