Designation | ISBT name | Haplotype | Phenotype | Mechanism | Alterations | First mention | Definitive publication |
DAR1 (weak D type 4.2.0) | RHD*09.01.00 RHD*DAR1.00 | cDe | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) | 1998 | 1999 |
DAR(CE2:V50V-S68N) | RHD*09.06 RHD*DAR6 RHD*DAR(SE2:v50V-S68N) | cDe | Partial D | Complex changes | 1025T>C (I342T) 150T>C 178A>C (I60L) 201G>A 203G>A (S68N) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2013 | |
DAR(T203A) | RHD*09.01 RHD*DAR | cDe | Partial D | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 607A>G (T203A) 667T>G (F223V) 744C>T 957 G>A | 2012 | 2012 |
DAR-E | RHD*09.02 RHD*DAR2 | cDe | Partial D weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 957 G>A | 2006 | 2006 |
DAR2.1 | RHD*09.02.01 RHD*DAR2.01 | not reported | Partial D | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 697G>C (E233Q) 744C>T 957 G>A | ||
DFV | RHD*08.01 RHD*DFV | multiple | Partial D | Single missense mutation | 667T>G (F223V) | 2002 | 2002 |
DFV.1 | cDe | weakened D expression | Single missense mutation | 667T>G (F223V) 819G>A | 2013 | 2014 | |
DOL-1 | RHD*12.01 RHD*DOL1 | cDe | Partial D | Multiple missense mutations | 509T>C (M170T) 667T>G (F223V) | 1999 | 2009 |
DOL-2 | RHD*12.02 RHD*DOL2 | not reported | Partial D | Multiple missense mutations | 1132C>G (L378V) 509T>C (M170T) 667T>G (F223V) | 2005 | 2009 |
DOL-3 | RHD*12.03 RHD*DOL3 | not reported | Partial D | Multiple missense mutations | 410C>T (A137V) 509T>C (M170T) 667T>G (F223V) | 2005 | |
DTO | RHD*30 RHD*DTO | not reported | weakened D expression Partial D | Multiple missense mutations | 667T>G (F223V) 674C>T (S225F) | 2005 | 2005 |
RHD psi | RHD*08N.01 RHD*Pseudogene | cDe | D negative | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 807T>G (Y269X) IVS3-19 dupl 37 | 2000 | 2000 |
RHD(F223V,G278V) | not reported | D positive (no further data) | Multiple missense mutations | 667T>G (F223V) 833G>T (G278V) | 2012 | 2012 | |
RHD(F223V,K267M) | not reported | Multiple missense mutations | 667T>G (F223V) 800A>T (K267M) | 2017 | |||
weak D type 4.4 | not reported | weak D type | Multiple missense mutations | 594A>T (K198N) 602C>G (T201R) 667T>G (F223V) 819G>A | 2016 | ||
RHD(M218I, F223V, S225F,Y269X) | not reported | D negative | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 807T>G (Y269X) | 2009 | ||
RHD(T201R)-CE(5)-D(I342T) | not reported | weakened D expression Partial D | Complex changes | 1025T>C (I342T) 602C>G (T201R) Hybrid RHCE(5) | 2018 | 2018 | |
RHD(T201R,F223V,G307R) | not reported | D positive (no further data) | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A 919G>A (G307R) | 2012 | 2012 | |
weak D type 4.5 | not reported | weak D type | Multiple missense mutations | 1063G>A (G355S) 602C>G (T201R) 667T>G (F223V) 819G>A | 2016 | ||
RHD(T201R,F223V,K264N,A273A) | not reported | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 792G>T (K264N) 819G>A | 2016 | |||
RHD-RHCE(3)--weak D type 4.0 | RHD*01N.72 | not reported | D negative | hybrid allele | 602C>G (T201R) 667T>G (F223V) 819G>A Hybrid RHCE(3) | ||
RHDpsi-OT1 | cDe | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 835G>A (V279M) IVS3-19 dupl 37 IVS7-214ins ACAG | 2012 | |||
weak D type 29 | RHD*01W.29 RHD*weak D type 29 | cDe | weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 178A>C (I60L) 201G>A 203G>A (S68N) 594A>T (K198N) 667T>G (F223V) 744C>T 957 G>A | 2003 | 2003 |
RHD(I60L,S68N,K198N,F223V,G314V,I342T) | not reported | weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 178A>C (I60L) 201G>A 203G>A (S68N) 594A>T (K198N) 667T>G (F223V) 744C>T 941G>T (G314V) | 2010 | ||
weak D type 4.0 | RHD*09.03.01 RHD*DAR3 | cDe | weak D type weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A | 1999 | 1999 |
weak D type 4.0.1 | RHD*09.03 RHD*DAR3 | cDe | weak D type weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) | ||
weak D type 4.1 | RHD*09.04 RHD*DAR4 | cDe | weak D type weakened D expression | Multiple missense mutations | 48G>C (W16C) 602C>G (T201R) 667T>G (F223V) 819G>A | 2000 | 2000 |
weak D type 4.2.1 (DAR1.1) | RHD*09.01.01 RHD*DAR1.01 RHD*weak 4.2 | cDe | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 957 G>A | 2000 | 2000 |
weak D type 4.2.2 (DAR1.2) | RHD*09.01.02 | cDe | Partial D weak D type weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T 957 G>A | 2000 | 2000 |
weak D type 4.2.3 (DAR1.3) | RHD*09.01.03 RHD*DAR1.03 | cDe | weak D type Partial D weakened D expression | Multiple missense mutations | 1025T>C (I342T) 602C>G (T201R) 667T>G (F223V) 744C>T | 2008 | |
weak D type 4.3 | RHD*09. 05 RHD*weak 4.3 | cDe | weak D type DEL weakened D expression Partial D | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 819G>A 872C>G (P291R) | 2004 |