| Designation | ISBT name | Cluster | Haplotype | Mechanism | Alterations | First mention | Definitive publication |
| Co(A45T) | main Cluster | Colton | Single missense mutation | 133G>A (A45T) | 2010 | 2010 | |
| CO(Q47R) | CO*01.-04 | main cluster | Colton | Single missense mutation | 140A>G (Q47R) | 2002 | 2010 |
| CO*01N.03 | CO*01N.03 | main cluster | Colton | Single missense mutation | 576C>A (N192K) | 1999 | 1999 |
| CO*01N.04 | CO*01N.04 | main cluster | Colton | Short deletion | 232delG | 2001 | 2001 |
| CO*01N.05 | CO*01N.05 | main cluster | Colton | Single missense mutation | 112C>T (P38S) | 2009 | 2010 |
| CO*01N.06 | CO*01N.06 | main cluster | Colton | Short deletion | 601delG | 2012 | 2012 |
| CO*02 | CO*02 CO*B | main cluster | Colton | Single missense mutation | 134C>T (A45V) | 1994 | 1994 |
| CO*M.01 | CO*M.01 | main cluster | Colton | Single missense mutation | 113C>T (P38L) | 1994 | 1994 |
| CO*N.01 | CO*N.01 | main cluster | Colton | large deletion | del Exon 1 | 1994 | 1994 |
| CO*N.02 | main cluster | Colton | Short insertion | 307insT | 1994 | 1994 |