Co(A45T)

Structure

Co(A45T)

Key changes from standard allele

133G>A (A45T)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard CO"

c.133 G>A

Amino acid changes relative to standard protein

Ala to Thr at codon 45

A45T

ISBT group

Co3 positive

Phenotype characterization and grouping

Co(b+); Co(a-)

Descriptions

First full publication: 2010 Arnaud L et. al. Transfusion. 2010 Oct;50(10):2106-16. doi: 10.1111/j.1537-2995.2010.02687.x. Epub

Serology

Co(a-b+) in expression study Arnaud L et. al. Transfusion. 2010 Oct;50(10):2106-16. doi: 10.1111/j.1537-2995.2010.02687.x. Epub

Observations

No data

Additional comments

The mutation causes an Co(a-b+) phenotype

Last update: 2015-06-13 (yyyy-MM-dd)