Designation | ISBT name | Cluster | Phenotype | Mechanism | Alterations | First mention | Definitive publication |
DBS-1 | RHD*13.01 RHD*DBS1 | Eurasian D cluster | Partial D | hybrid allele | Hybrid RHcE[226P](5:667-5:800) | 2001 | 2001 |
DBS-2 | RHD*13.02 RHD*DBS2 RHD*16.03 | Eurasian D cluster | Partial D | hybrid allele | Hybrid RHcE[226P](5:667-5:697) | 2009 | 2012 |
DBU | RHD*41 RHD*DBU RHD*01EL.23 | Eurasian D cluster | DEL Partial D | hybrid allele | Hybrid RHcE[226P](5-7) | 2008 | 2009 |
DCS-1 | RHD*16.01 RHD*DCS1 | Eurasian D cluster | Partial D | hybrid allele | 667T>G (F223V) 676G>C (A226P) | 1999 | 2008 |
DCS-2 | RHD*16.02 RHD*DCS2 | Eurasian D cluster | Partial D | Single missense mutation | 676G>C (A226P) | 2008 | 2008 |
DHMi | RHD*19 RHD*DHMi | Eurasian D cluster | Partial D | Single missense mutation | 848C>T (T283I) | 1996 | |
DHMii | Eurasian D cluster | Partial D | hybrid allele | 1996 | |||
DIM | RHD*34 RHD*DIM | Eurasian D cluster | Partial D weakened D expression | Single missense mutation | 854G>A (C285Y) | 2000 | 2000 |
DIV type 5 | RHD*04.05 RHD*DIV.5 | Eurasian D cluster | Partial D D category | hybrid allele | Hybrid RHCE(7-9) | 2000 | 2000 |
DKK | RHD*45 RHD*DKK | Eurasian D cluster | Partial D | hybrid allele | Hybrid RHCE(2-3) | 2000 | 2001 |
DLX | RHD*46 RHD*DLX | Eurasian D cluster | Partial D | Complex changes | 667T>G (F223V) Hybrid RHCE(5:712-6) | 2012 | 2012 |
DNAK | RHD*24 RHD*DNAK | Eurasian D cluster | Partial D | Single missense mutation | 1070G>A (G357D) | 2005 | |
DNU | RHD*26 RHD*DNU | Eurasian D cluster | Partial D | Single missense mutation | 1057G>A (G353R) | 1997 | 1997 |
DVI type 1 | RHD*06.01 RHD*DVI.1 | Eurasian D cluster | D category Partial D | hybrid allele | Hybrid RHcE[226P](4-5) | 1997 | 1997 |
RHCE(1-3)-RHD(4-10) | RHD*01N.43 | Eurasian D cluster | D negative | hybrid allele | Hybrid RHCE(1-3) | 2004 | 2009 |
RHCE(1-9)-RHD | RHD*01N.02 | Eurasian D cluster | D negative | hybrid allele | Hybrid RHCE(1-9) | 2001 | 2001 |
RHD(IVS1+1G>T) | RHD*01EL.31 RHD*DEL31 | Eurasian D cluster | DEL | Splice site mutation | IVS1+1G>T | 2014 | 2014 |
RHD(711del C) | RHD*01N.16 | Eurasian D cluster | D negative | Short deletion | 711del C | 2002 | 2002 |
weak D type 95 | RHD* 01W.95 RHD*weak D type 95 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 730G>C (A244P) | 2013 | 2013 |
RHD(D404H) | RHD*01EL.29 RHD*DEL29 | Eurasian D cluster | DEL | Single missense mutation | 1210G>C (D404H) | 2012 | |
RHD(IVS3+2T>A) | RHD*01EL.09 RHD*DEL9 | Eurasian D cluster | D negative | Splice site mutation | IVS3+2T>A | 2008 | 2009 |
RHD(IVS4-2A>C) | RHD*54 | Eurasian D cluster | Partial D | Splice site mutation | IVS4-2A>C | 2014 | 2014 |
RHD(IVS8+6T>C) | Eurasian D cluster | weakened D expression | Splice site mutation | IVS8+6T>C | 2012 | ||
RHD(L153P) | RHD*01EL.12 RHD*DEL12 | Eurasian D cluster | DEL | Single missense mutation | 458T>C (L153P) | 2004 | 2009 |
weak D type 83 | RHD* 01W.83 RHD*weak D type 83 | Eurasian D cluster | weakened D expression | Single missense mutation | 1238T>G (L413W) | 2012 | |
RHD(M1T) | Eurasian D cluster | Loss of start codon | 2T>C (M1T) | 2015 | 2015 | ||
RHD(S103P) | RHD*39 | Eurasian D cluster | Partial D | Single missense mutation | 307T>C (S103P) | 1996 | 1996 |
weak D type 98 | RHD* 01W.98 RHD*weak D type 98 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 751A>C (T251P) | 2013 | 2013 |
weak D type 2.2 | RHD*01W.2.2 RHD*weak D type 2.2 | Eurasian D cluster | weak D type weakened D expression | Multiple missense mutations | 1154G>C (G385A) 916G>A (V306I) 932A>G (Y311C) | 2014 | 2014 |
RHD(W16R) | RHD*01EL.43 RHD*DEL43 | Eurasian D cluster | DEL | Single missense mutation | 46T>C (W16R) | 2012 | |
weak D type 106 | RHD* 01W.106 RHD*weak D type 106 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 220T>G (W74G) | 2015 | 2015 |
RHD(Y343X) | RHD*01N.40 | Eurasian D cluster | D negative | Nonsense mutation | 1029C>A (Y343X) | 2012 | 2013 |
RHD(Y401X) | RHD*01N.22 RHD*DEL17 RHD*01EL.17 | Eurasian D cluster | D negative | Nonsense mutation | 1203T>A (Y401X) | 2004 | 2005 |
RHD-RHCE(4-7)-RHD | RHD*01N.07 | Eurasian D cluster | D negative DEL | hybrid allele | Hybrid RHCE(4-7) | 1996 | 1996 |
RHD-RHCE(4-7)-RHD1 | RHD*01N.07 | Eurasian D cluster | D negative | hybrid allele | Hybrid RHCE(4-7) | ||
RHD-RHCE(4-7)-RHD2 | RHD*01N.07 | Eurasian D cluster | D negative | hybrid allele | Hybrid RHCE(4-7) | ||
RHD-RHCE(7)-RHD | RHD*58 | Eurasian D cluster | Partial D D category | hybrid allele | Hybrid RHCE(7) | 2012 | |
weak D type 10 | RHD*01W.10 RHD*weak D type 10 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 1177T>C (W393R) | 1999 | 1999 |
weak D type 14 | RHD*01W.14 RHD*weak D type 14 | Eurasian D cluster | weak D type weakened D expression | Multiple missense mutations | 544T>A (S182T) 594A>T (K198N) 602C>G (T201R) | 1999 | 1999 |
weak D type 15 | RHD*15 RHD*weak partial 15 | Eurasian D cluster | weak D type weakened D expression Partial D | Single missense mutation | 845G>A (G282D) | 1999 | 1999 |
weak D type 16 | RHD*01W.16 RHD*weak D type 16 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 658T>C (W220R) | 1999 | 1999 |
weak D type 2 | RHD*01W.2 RHD*weak D type 2 | Eurasian D cluster | weak D type weakened D expression | Missense (splice site affected) | 1154G>C (G385A) | 1999 | 1999 |
weak D type 2.1 | RHD*01W.2.1 RHD*weak D type 2.1 | Eurasian D cluster | weak D type weakened D expression | Multiple missense mutations | 1154G>C (G385A) 301T>A (F101I) | 2009 | |
weak D type 20 | RHD*01W.20 RHD*weak D type 20 | Eurasian D cluster | weak D type | Single missense mutation | 1250T>C (F417S) | 2000 | 2006 |
weak D type 48 | RHD*01W.48 RHD*weak D type 48 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 182G>T (G61V) | 2005 | |
weak D type 5 | RHD*01W.5 RHD*weak D type 5 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 446C>A (A149D) | 1999 | 1999 |
weak D type 54 | RHD*01W.54 RHD*weak D type 54 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 365C>T (S122L) | ||
weak D type 55 | RHD*01W.55 RHD*weak D type 55 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 895C>G (L299V) | 2007 | |
weak D type 67 | RHD*01W.67 RHD*weak D type 67 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 722C>T (T241I) | 2008 | |
weak D type 88 | RHD* 01W.88 RHD*weak D type 88 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 182G>C (G61A) | 2014 | |
weak D type 9 | RHD*01W.9 RHD*weak D type 9 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 880G>C (A294P) | 1999 | 1999 |
weak D type 93 | RHD* 01W.93 RHD*weak D type 93 | Eurasian D cluster | weak D type weakened D expression | Single missense mutation | 359C>A (A120D) | 2016 | |
weak RHD(IVS3+3G>C) | Eurasian D cluster | weakened D expression | Splice site mutation | IVS3+3G>C | 2008 | 2013 |