Designation | ISBT name | Cluster | Haplotype | Mechanism | Alterations | First mention | Definitive publication |
RHD(1227G>A) | RHD*01EL.01 RHD*DEL1 | Eurasian D cluster | CDe | Splice site mutation | 1227G>A | 2001 | 2001 |
RHD(M1I) | RHD*01EL.02 RHD*DEL2 | Eurasian D cluster | not reported | Loss of start codon | 3G>A (M1I) | 2006 | 2006 |
RHD(L18P) | RHD*01EL.03 RHD*DEL3 | Eurasian D cluster | not reported | Single missense mutation | 53T>C (L18P) | 2006 | 2006 |
RHD(147del A) | RHD*01EL.04 RHD*DEL4 | Eurasian D cluster | CDe | Short deletion | 147del A IVS1+6del A | 2004 | 2009 |
RHD(IVS1+1G>A) | RHD*01EL.05 RHD*DEL5 | Eurasian D cluster | not reported | Splice site mutation | IVS1+1G>A | 2001 | |
RHD(L84P) | RHD*01EL.06 RHD*DEL6 | Eurasian D cluster | not reported | Single missense mutation | 251T>C (L84P) | 2006 | 2006 |
RHD(A137E) | RHD*01EL.07 RHD*DEL7 | Eurasian D cluster | CDe | Single missense mutation | 410C>A (A137E) | 2006 | 2009 |
RHD(IVS3+1G>A) | RHD*01EL.08 RHD*DEL8 | Eurasian D cluster | CDe | Splice site mutation | IVS3+1G>A | 2001 | 2001 |
RHD(IVS3+2T>A) | RHD*01EL.09 RHD*DEL9 | Eurasian D cluster | cDE | Splice site mutation | IVS3+2T>A | 2008 | 2009 |
RHD(W408R) | RHD*01EL.10 RHD*DEL10 | Eurasian D cluster | CDe | Single missense mutation | 1222T>C (W408R) | 2005 | 2005 |
RHD(X418L) | RHD*01EL.11 RHD*DEL11 | Eurasian D cluster | CDe | Loss of stop codon | X418L (1252ins T) | 2005 | 2005 |
RHD(L153P) | RHD*01EL.12 RHD*DEL12 | Eurasian D cluster | cDE | Single missense mutation | 458T>C (L153P) | 2004 | 2009 |
RHD(786del A) | RHD*01EL.13 RHD*DEL13 | Eurasian D cluster | CDe | Short deletion | 786del A | 2004 | 2009 |
RHD(IVS4+5G>T) | RHD*01EL.14 RHD*DEL14 | Eurasian D cluster | CDe | Splice site mutation | IVS4+5G>T | 2010 | 2013 |
RHD(G308X) | RHD*01EL.15 RHD*DEL15 RHD*01N.52 | Eurasian D cluster | CDe | Nonsense mutation | 922G>T (G308X) | 2010 | |
RHD(G212R) | RHD*01EL.16 RHD*DEL16 | Eurasian D cluster | cDe | Missense (splice site affected) | 634G>C (G212R) | 2008 | 2009 |
RHD(93insT) | RHD*01EL.18 RHD*DEL18 RHD*01N.50 | Eurasian D cluster | CDe | Short insertion | 93insT | 2008 | 2008 |
RHD(IVS4-2A>G) | RHD*01EL.19 RHD*DEL19 | Eurasian D cluster | not reported | Splice site mutation | IVS4-2A>G | 2010 | 2011 |
RHD(IVS8-8T>A) | RHD*01EL.20 RHD*DEL20 | Eurasian D cluster | not reported | Splice site mutation | IVS8-8T>A | 2007 | 2007 |
RHD(IVS1+5G>C) | RHD*01EL.21 RHD*DEL21 | Eurasian D cluster | not reported | Splice site mutation | IVS1+5G>C | 2013 | |
DEL RHD(A280T) | RHD*01EL.24 RHD*DEL24 | Eurasian D cluster | not reported | Single missense mutation | 838G>A (A280T) | 2014 | 2014 |
DEL RHD(X418K) | RHD*01EL.25 RHD*DEL25 | Eurasian D cluster | CDe | Loss of stop codon | 1252T>A (X418K) | 2015 | 2015 |
RHD(1248insG) | RHD*01EL.26 RHD*DEL26 | Eurasian D cluster | CDe | Short insertion | 1248insG | 2014 | 2014 |
RHD(993delC) | RHD*01EL.28 RHD*DEL28 | Eurasian D cluster | not reported | Short deletion | 993delC | 2014 | |
RHD(D404H) | RHD*01EL.29 RHD*DEL29 | Eurasian D cluster | cDE | Single missense mutation | 1210G>C (D404H) | 2012 | |
RHD(del Ex8) | RHD*01EL.30 RHD*DEL30 | Eurasian D cluster | not reported | large deletion | del Ex8 | 2007 | 2007 |
RHD(IVS1+1G>T) | RHD*01EL.31 RHD*DEL31 | Eurasian D cluster | cDE | Splice site mutation | IVS1+1G>T | 2014 | 2014 |
RHD(IVS1-29G>C) | RHD*01EL.32 RHD*DEL32 | Eurasian D cluster | CDe | Intron polymorphism | IVS1-29G>C | 2012 | |
RHD(IVS2-2A>G) | RHD*01EL.33 RHD*DEL33 | Eurasian D cluster | not reported | Splice site mutation | IVS2-2A>G | 2011 | 2011 |
RHD(IVS7+152C>A,1227G>A) | RHD*01EL.36 RHD*DEL36 | Eurasian D cluster | CDe | Splice site mutation | 1227G>A IVS7+152C>A | 2002 | 2002 |
RHD(IVS8-31C>T) | RHD*01EL.37 RHD*DEL37 | Eurasian D cluster | not reported | Intron polymorphism | IVS8-31C>T | 2012 | |
RHD(L337R) | RHD*01EL.38 RHD*DEL38 RHD*01N.57 | Eurasian D cluster | CDe | Single missense mutation | 1010T>G (L337R) | 2014 | 2014 |
RHD(L38X) | RHD*01EL.39 RHD*DEL39 | Eurasian D cluster | not reported | Nonsense mutation | 113T>A (L38X) | 2010 | |
RHD(L93R) | RHD*01EL.40 RHD*DEL40 | Eurasian D cluster | CDe | Single missense mutation | 278T>G (L93R) | 2014 | 2014 |
RHD(P291R) | RHD*01EL.41 RHD*DEL41 | Eurasian D cluster | CDe | Single missense mutation | 872C>G (P291R) | 2012 | |
RHD(S112T) | RHD*01EL.42 RHD*DEL42 | Eurasian D cluster | not reported | Missense (splice site affected) | 335G>C (S112T) IVS1-29G>C | 2012 | |
RHD(W16R) | RHD*01EL.43 RHD*DEL43 | Eurasian D cluster | cDE | Single missense mutation | 46T>C (W16R) | 2012 | |
RHD-RHCE(4-9)-RHD | RHD*01EL.44 RHD*DEL44 | Eurasian D cluster | CDe | hybrid allele | Hybrid RHCE(4-9) | 2009 | 2009 |
RHD(T241P) | RHD*01EL.45 RHD*DEL45 | Eurasian D cluster | not reported | Single missense mutation | 721A>C (T241P) | ||
weak D type 94 | RHD* 01W.94 RHD*weak D type 94 RHD*01EL.46 RHD*DEL46 | Eurasian D cluster | CDe | Single missense mutation | 884T>C (M295T) | 2012 | 2013 |
DBU | RHD*41 RHD*DBU RHD*01EL.23 RHD*DEL23 | Eurasian D cluster | cDE | hybrid allele | Hybrid RHcE[226P](5-7) | 2008 | 2009 |
RHD(IVS2-2delA) | RHD*53 RHD*01EL.22 RHD*DEL22 | Eurasian D cluster | not reported | Short deletion | IVS2-2delA | 2013 |