RHD(93insT)

Structure

RHD(93dupT)

Key changes from standard allele

93insT

ISBT allele designation

RHD*01EL.18
RHD*DEL18
RHD*01N.50

Nucleotide changes relative to "standard RHD"

c.93 insT

Amino acid changes relative to standard protein

ISBT group

DEL

Phenotype characterization and grouping

DEL; D negative

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2008 EU447199 (submitted 2008-02-04, released 2008-06-12)

First full publication: 2008 Muller SP et. al. Transfusion. 2008 Nov;48(11):2292-301. Epub 2008 Aug 7.

Other relevant descriptions:
Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71. (submitted 2008-05-23)
AM998541 (submitted 2008-05-09, released 2008-08-02)
FN998905 (submitted 2010-07-06, released 2010-07-17)
Christiansen M et. al. Transfusion. 2010 Jul;50(7):1460-4. Epub 2010 Apr 23.
GU211346 (submitted 2009-11-17, released 2012-11-09)

Serology

Anti-D in 3 of 82 D negative recipients of RHD(93insT) units; immunization by D positive apheresis platelets cannot be excluded. St-Louis R & et al. Vox Sanguinis (2012) 103 (Suppl. 1), 1â??271 Abstract 3C-S8-03
DEL Wagner FF & et al. Vox Sanguinis (2012) 103 (Suppl. 1), 1â??271 Abstract 3C-S8-04

Observations

Canada (general): 7 of about 4000 D negative donors St-Louis R & et al. Vox Sanguinis (2012) 103 (Suppl. 1), 1â??271 Abstract 3C-S8-03
Denmark (general): Christiansen M et. al. Transfusion. 2010 Jul;50(7):1460-4. Epub 2010 Apr 23.
Northern Germany: FN998905
Northern Germany: Wagner FF & et al. Vox Sanguinis (2012) 103 (Suppl. 1), 1â??271 Abstract 3C-S8-04
South-Western Germany: Flegel WA et. al. Transfusion. 2009 Mar;49(3):465-71.

Additional comments

Last update: 2018-02-17 (yyyy-MM-dd)