No designation assigned
Eurasian D cluster
First full publication: 2009 Li Q et. al. Vox Sang. 2009 Aug;97(2):139-46. Epub 2009 Mar 30.
Silvy M et. al. Transfusion. 2012 Feb 10.
France (general): 3 samples Silvy M et. al. Transfusion. 2012 Feb 10.
China (general): Li Q et. al. Vox Sang. 2009 Aug;97(2):139-46. Epub 2009 Mar 30.
Poland (general): Orzinska A et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2945-53. doi: 10.1111
The sequence of the RHD exons was verified by sequencing. The cause of the DEL phenotype despite a normal coding sequence is unknown.
Suspiciously, recently an allele with a deletion of RHD exon 10 has been described that would yield the described PCR pattern and explain the weakening of D antigen. Hence, this allele might be obsolete.
Last update: 2012-03-28 (yyyy-MM-dd)