RHD(delEx10)

Structure

RHD(IVS9-4064del5406)

Key changes from standard allele

delEx10

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

1228-4064 del5406

Amino acid changes relative to standard protein

not applicable

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2012 JN696682 (submitted 2011-09-16, released 2012-02-29)

First full publication: 2012 Fichou Y et. al. Transfusion. 2012 Mar 15.

ISBT group

Phenotype characterization and grouping

Serology

weak D phenotype; no anti-D among 61 probands Fichou Y et. al. Transfusion. 2012 Mar 15.

Observations

France (general): 61 probands, possible founder mutation Fichou Y et. al. Transfusion. 2012 Mar 15.
Poland (general): I`m not quite sure whether the description refers to this allele. At least exon 10 seemed to lack from RNA Orzinska A et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2945-53. doi: 10.1111

Additional comments

This allele may explain the PCR pattern previously reported as RHD-RHCE(10).

Last update: 2016-08-28 (yyyy-MM-dd)