ces

Structure

Key changes from standard allele

48G>C (W16C)
733C>G (L245V)

ISBT allele designation

RHCE*01.20.02
RHCE*ce.20.02
RHCE*ceVS.02

Nucleotide changes relative to "standard RHCE"

c.[48 G>C;733 C>G]

Amino acid changes relative to standard protein

W16C, L245V

ISBT group

ce

Phenotype characterization and grouping

c positive; e positive; VS positive; V positive

Haplotype (typical)

cDe

Allele cluster

ces Cluster

Descriptions

First full publication: 1997 Faas BH et. al. Transfusion. 1997 Jan;37(1):38-44. (submitted 1996-01-22)

Other relevant descriptions:
First description of 245V in VS-positive samples. Blunt T et. al. Vox Sang. 1994;67(4):397-401.

Serology

VS expression is associated with Val at codon 245 Blunt T et. al. Vox Sang. 1994;67(4):397-401.
245V is sufficient for VS expression Faas BH et. al. Transfusion. 1997 Jan;37(1):38-44.
associated with VS+, V+ phenotype Daniels GL et. al. Transfusion. 1998 Oct;38(10):951-8.

Observations

Dutch Black population: Daniels GL et. al. Transfusion. 1998 Oct;38(10):951-8.
South Africa (general): Daniels GL et. al. Transfusion. 1998 Oct;38(10):951-8.

Related Alleles

ceS [RHCE(W16C,L245V,G336C)]

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)