weak D type 87

Structure

RHD(I125N)

Key changes from standard allele

374T>A (I125N)

ISBT allele designation

RHD* 01W.87
RHD*weak D type 87

Nucleotide changes relative to "standard RHD"

c.374 T>A

Amino acid changes relative to standard protein

Ile to Asn at codon 125

I125N

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2014 KM061058 (submitted 2014-06-26, released 2014-10-01)

First full publication: 2015 Flesch BK et. al. Transfusion. 2015 Feb 3. doi: 10.1111/trf.13004.

Serology

weakened D expression Flesch BK et. al. Transfusion. 2015 Feb 3. doi: 10.1111/trf.13004.

Observations

Germany (general): Flesch BK et. al. Transfusion. 2015 Feb 3. doi: 10.1111/trf.13004.

Additional comments

Last update: 2017-02-12 (yyyy-MM-dd)