weak D type 31

Structure

RHD(P6L)

Key changes from standard allele

17C>T (P6L)

ISBT allele designation

RHD*01W.31
RHD*weak D type 31

Nucleotide changes relative to "standard RHD"

c.17 C>T

Amino acid changes relative to standard protein

Pro to Leu at codon 6

P6L

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2004 AJ557803 (submitted 2003-04-28, released 2004-01-05)

First full publication: 2005 Kormoczi GF et. al. Transfusion. 2005 Oct;45(10):1574-80.

Serology

Kormoczi GF et. al. Transfusion. 2005 Oct;45(10):1574-80.

Observations

No data

Additional comments

One family known. This allele erroneously had been listed as RHD(L6P) in the old RhesusBase, an error which perpetuated into the first draft of the ISBT allele nomenclature list.

Last update: 2012-03-25 (yyyy-MM-dd)