| Designation | ISBT name | Cluster | Haplotype | Mechanism | Alterations | First mention | Definitive publication |
| D186T | DIVa cluster | not reported | Single missense mutation | 186G>T (L62F) | 2012 | ||
| DIIIa150C | DIVa cluster | not reported | Multiple missense mutations | 150T>C 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 602C>G (T201R) 667T>G (F223V) 819G>A | 2012 | ||
| RHD(147A>G) | Eurasian D cluster | not reported | Silent mutation | 147A>G (Q49Q) | 2011 | 2012 | |
| RHD(1347A>G) | Eurasian D cluster | cDe | untranslated region | 1347A>G | 2003 | 2003 | |
| RHD(27del13) | Eurasian D cluster | not reported | Short deletion | 27del13 | 2012 | ||
| D674 | Eurasian D cluster | not reported | Single missense mutation | 674C>T (S225F) | 2002 | 2002 | |
| DAU-0.1 | RHD*10.00.01 RHD*DAU0.01 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 579G>A | 2003 | 2003 |
| DAU-0.2 | RHD*10.00.02 RHD*DAU0.02 | Eurasian D cluster | not reported | Complex changes | 1136C>T (T379M) 150T>C | ||
| DAU-12 | RHD*10.12 RHD*DAU12 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 542T>C (L181P) | 2012 | |
| DAU-13 | RHD*10.13 RHD*DAU13 | DAU cluster | cDe | Multiple missense mutations | 1136C>T (T379M) 48G>C (W16C) | 2013 | |
| DBO-3 | Eurasian D cluster | not reported | Single missense mutation | 968C>A (P323H) | 2006 | ||
| DIII type 4.2 | RHD*03.04.02 RHD*DII.04.02 | Eurasian D cluster | not reported | hybrid allele | 186G>T (L62F) 307T>C (S103P) 410C>T (A137V) 455A>C (N152T) | ||
| DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D | DIVa cluster | not reported | hybrid allele | 1006G>T (G336C) 410C>T (A137V) 455A>C (N152T) 48G>C (W16C) Hybrid RHCE(2) Hybrid RHCE[245V](4-7) | 2017 | ||
| DIV(S103P) | DIVa cluster | cDe | Multiple missense mutations | 186G>T (L62F) 307T>C (S103P) 410C>T (A137V) 455A>C (N152T) | 2013 | ||
| DIVa-like | RHD*04.01.02 | Eurasian D cluster | not reported | hybrid allele | 1048G>C (D350H) 186G>T (L62F) 410C>T (A137V) 455A>C (N152T) 667T>G (F223V) | ||
| DMA | RHD*35 RHD*DMA | Eurasian D cluster | cDe | Single missense mutation | 621G>C (L207F) | 2003 | 2003 |
| RHD delEx3 type 1 | Eurasian D cluster | not reported | large deletion | 335+649del10625 | 2017 | ||
| RHD(1026insAC) | Eurasian D cluster | not reported | Short insertion | 1026insAC | 2014 | ||
| RHD(1067insA) | Eurasian D cluster | not reported | Short insertion | 1067insA | 2017 | ||
| RHD(1166delA) | Eurasian D cluster | not reported | Short deletion | 1166delA | 2013 | ||
| RHD(1174delA) | RHD*01N.66 | Eurasian D cluster | not reported | Short deletion | 1174delA | ||
| RHD(1209delT) | Eurasian D cluster | not reported | Short deletion | 1209delT | 2014 | ||
| RHD(124delAA) | RHD*01N.65 | Eurasian D cluster | not reported | Short deletion | 124delAA | ||
| RHD(255G>A, 1227G>A,) | Eurasian D cluster | not reported | Single missense mutation | 1227G>A 255G>A (A85A) | 2017 | ||
| RHD(356de11) | Eurasian D cluster | not reported | Short deletion | 356del11 | 2012 | ||
| RHD(384T>C) | Eurasian D cluster | not reported | Silent mutation | 384T>C | |||
| RHD(396insGG) | Eurasian D cluster | not reported | Short insertion | 396insGG | 2016 | ||
| RHD(510insG) | Eurasian D cluster | not reported | Short insertion | 510insG | 2015 | ||
| RHD(53dekT) | Eurasian D cluster | not reported | Single missense mutation | 53dekT | 2016 | ||
| RHD(581insG) | RHD*01N.75 RHD*581_582insG | Eurasian D cluster | not reported | Short insertion | 581insG | ||
| RHD(60L,S230I) | RHD*60 | Eurasian D cluster | not reported | Single missense mutation | 178A>C (I60L) 689G>T (S230I) | ||
| RHD(683del16) | Eurasian D cluster | not reported | Short deletion | 683del16 | 2013 | ||
| RHD(79delCTC) | Eurasian D cluster | not reported | In frame deletion | 79delCTC | 2016 | ||
| RHD(843G>T) | Eurasian D cluster | not reported | Silent mutation | 843G>T | 2017 | ||
| RHD(9393A>C) | Eurasian D cluster | not reported | Splice site mutation | IVS6+3A>C | 2017 | ||
| RHD(939G>C) | Eurasian D cluster | not reported | Splice site mutation | 939G>C | 2017 | ||
| RHD(993delC) | RHD*01EL.28 RHD*DEL28 | Eurasian D cluster | not reported | Short deletion | 993delC | 2014 | |
| RHD(A137V,N152T)-CE(4-6)-D(7-10) | DIVa cluster | not reported | hybrid allele | 410C>T (A137V) 455A>C (N152T) Hybrid RHCE(4-6) | 2016 | ||
| RHD(A176T) | Eurasian D cluster | not reported | Single missense mutation | 526G>A (A176T) | 2015 | 2015 | |
| RHD(A237D) | Eurasian D cluster | not reported | Single missense mutation | 710C>A (A237D) | 2010 | ||
| RHD(D350H) | Eurasian D cluster | not reported | Single missense mutation | 1048G>C (D350H) | 2013 | ||
| RHD(D40G) | Eurasian D cluster | not reported | Single missense mutation | 119A>G (D40G) | 2016 | ||
| RHD(E340G) | Eurasian D cluster | not reported | Single missense mutation | 1019A>G (E340G) | 2013 | ||
| RHD(E369K) | Eurasian D cluster | not reported | Single missense mutation | c.1105G>A (Glu369Lys) | 2019 | ||
| RHD(F179S) | Eurasian D cluster | not reported | Single missense mutation | 536T>C (F179S) | 2012 | ||
| RHD(F223V,K267M) | weak D type 4 cluster | not reported | Multiple missense mutations | 667T>G (F223V) 800A>T (K267M) | 2017 | ||
| RHD(G151D) | Eurasian D cluster | not reported | Single missense mutation | 452G>A (G151D) | 2017 | 2017 | |
| RHD(G255R) | Eurasian D cluster | not reported | Single missense mutation | 763G>A (G255R) | 2012 | 2012 | |
| RHD(G263L,T379M) | DAU cluster | not reported | Multiple missense mutations | 1136C>T (T379M) 787GG>TT (G263L) | 2017 | ||
| RHD(G263R,A399T) | Eurasian D cluster | not reported | Multiple missense mutations | 1195G>A (A399T) 787G>A (G263R) | 2016 | ||
| RHD(G307R) | Eurasian D cluster | not reported | Single missense mutation | 919G>C (G307R) | 2016 | ||
| RHD(G308R) | Eurasian D cluster | not reported | Single missense mutation | 922G>A (G308R) | 2017 | ||
| RHD(G353V) | Eurasian D cluster | not reported | Single missense mutation | 1058G>T (G353V) | 2012 | 2012 | |
| RHD(G368R) | Eurasian D cluster | not reported | Single missense mutation | 1102G>A (G368R) | 2014 | ||
| RHD(G368W,D404E) | Eurasian D cluster | not reported | Multiple missense mutations | 1102G>T (G368W) 1212C>A (D404E) | 2015 | ||
| RHD(G381R) | Eurasian D cluster | not reported | Single missense mutation | 1141G>C (G381R) | 2017 | ||
| RHD(G385V) | Eurasian D cluster | not reported | Single missense mutation | 1154G>T (G385V) | 2016 | ||
| RHD(G96R) | Eurasian D cluster | not reported | Single missense mutation | 286G>C (G96R) | 2016 | ||
| RHD(H166D) | Eurasian D cluster | not reported | Single missense mutation | 496C>G (H166D) | 2016 | ||
| RHD(H72P,S73C) | Eurasian D cluster | not reported | Multiple missense mutations | 215AC>CA (72H>P) 217A>T (S73C) | 2016 | ||
| RHD(I60L) | Eurasian D cluster | not reported | Single missense mutation | 178A>C (I60L) | 2016 | ||
| RHD(I60V,S103P,F161S,L214F) | Eurasian D cluster | not reported | Multiple missense mutations | 178A>G (I60V) 307T>C (S103P) 482T>C (F161S) 640C>T (L214F) 966T>C | 2012 | ||
| RHD(IVS4+1G>A) | Eurasian D cluster | not reported | Splice site mutation | IVS4+1G>A | 2012 | ||
| RHD(IVS4+2T>A) | Eurasian D cluster | not reported | Splice site mutation | IVS4+2T>A | 2012 | ||
| RHD(IVS5+2T>A) | Eurasian D cluster | not reported | Splice site mutation | 2012 | |||
| RHD(IVS5-41delCTCT) | Eurasian D cluster | not reported | Intron polymorphism | 2012 | |||
| RHD(IVS7+1G>A) | Eurasian D cluster | not reported | Splice site mutation | IVS7+1G>A | 2016 | ||
| RHD(IVS7-1G>A) | RHD*01N.71 | Eurasian D cluster | not reported | Splice site mutation | IVS7-1G>A | ||
| RHD(IVS7-2A>C) | RHD*01N.81 RHD*1074-2C | Eurasian D cluster | not reported | Splice site mutation | IVS7-2A>C | 2011 | |
| RHD(IVS9-1G>A) | RHD*01N.77 RHD*1228-1A | Eurasian D cluster | CDe | Splice site mutation | IVS9-1G>A | 2014 | 2014 |
| RHD(K189N,S257F) | Eurasian D cluster | not reported | Multiple missense mutations | 567G>T (K189N) 770C>T (S257F) | 2016 | ||
| RHD(K235N) | Eurasian D cluster | not reported | Single missense mutation | 705G>T (K235N) | 2017 | ||
| RHD(K267M) | Eurasian D cluster | not reported | Single missense mutation | 800A>T (K267M) | 2016 | ||
| RHD(L110P)-CE(3-9)-D | Eurasian D cluster | CDe | Complex changes | 329T>C (L110P) Hybrid RHCE(3-9) | 2014 | 2014 | |
| RHD(L20P) | Eurasian D cluster | not reported | Single missense mutation | 59T>C (L20P) | 2017 | ||
| RHD(L228Q) | Eurasian D cluster | not reported | Single missense mutation | 683T>A (L228Q) | 2012 | 2012 | |
| RHD(L258S) | Eurasian D cluster | not reported | Single missense mutation | 773T>C (L258S) | 2017 | ||
| RHD(L297P) | Eurasian D cluster | not reported | Single missense mutation | 890T>C (L297P) | 2016 | ||
| RHD(L299P) | RHD*01N.79 RHD*896C | Eurasian D cluster | not reported | Single missense mutation | 896T>C (L299P) | 2011 | |
| RHD(L378P) | Eurasian D cluster | not reported | Single missense mutation | c.1133T>C (Leu378Pro) | 2019 | ||
| RHD(M155V) | Eurasian D cluster | not reported | Single missense mutation | 463A>G (M155V) | 2017 | ||
| RHD(M1T) | Eurasian D cluster | cDE | Loss of start codon | 2T>C (M1T) | 2015 | 2015 | |
| RHD(M1V,T379M) | RHD*10.15 RHD*DAU15 | DAU cluster | not reported | Complex changes | 1136C>T (T379M) 1A>G (M1?) | 2008 | |
| RHD(M1_S2insV,T379M) | DAU cluster | not reported | Complex changes | 1136C>T (T379M) 3_4insGTG (M1_S2insV) | 2008 | ||
| RHD(N135D) | Eurasian D cluster | not reported | Single missense mutation | 403A>G (N135D) | 2014 | ||
| RHD(N152T,V270G) | RHD*62 | Eurasian D cluster | not reported | Multiple missense mutations | 455A>C (N152T) 809T>G (V270G) | 2014 | |
| RHD(N240H) | Eurasian D cluster | not reported | Single missense mutation | 718A>C (N240H) | 2014 | ||
| RHD(P221R) | Eurasian D cluster | not reported | Single missense mutation | 662C>G (P221R) | 2016 | ||
| RHD(P231L) | Eurasian D cluster | not reported | Single missense mutation | 691CC>TT (P231L) | 2016 | ||
| RHD(P313P) | Eurasian D cluster | not reported | Splice site mutation | 939G>A | 2012 | 2012 | |
| RHD(Q89R) | Eurasian D cluster | not reported | Single missense mutation | 266A>G (Q89R) | 2014 | ||
| RHD(R10L) | Eurasian D cluster | not reported | Single missense mutation | 29G>T (R10L) | 2015 | ||
| RHD(R114Q,A399T) | Eurasian D cluster | not reported | Single missense mutation | 1195G>A (A399T) 341G>A (R114Q) | 2017 | ||
| RHD(S112I) | RHD*01N.68 | Eurasian D cluster | not reported | Single missense mutation | 335G>T (S112I) | 2012 | |
| RHD(S230I) | Eurasian D cluster | not reported | Single missense mutation | 689G>T (S230I) | 2016 | ||
| RHD(S230N) | Eurasian D cluster | not reported | Single missense mutation | 689G>A (S230N) | 2016 | ||
| RHD(S254L,T379M) | DAU cluster | not reported | Multiple missense mutations | 1136C>T (T379M) 761C>T (S254L) | 2017 | ||
| RHD(S266G,V270G) | Eurasian D cluster | not reported | Single missense mutation | 796A>G (S266G) 809T>G (V270G) | 2016 | ||
| RHD(T148R,T195M) | Eurasian D cluster | not reported | Multiple missense mutations | 443C>G (T148R) 584C>T (T195M) | 2017 | ||
| RHD(T201R,F223V,K264N,A273A) | weak D type 4 cluster | not reported | Multiple missense mutations | 602C>G (T201R) 667T>G (F223V) 792G>T (K264N) 819G>A | 2016 | ||
| RHD(T201R,V270G) | Eurasian D cluster | not reported | Multiple missense mutations | 602C>G (T201R) 809T>G (V270G) | 2017 | ||
| RHD(T241P) | RHD*01EL.45 RHD*DEL45 | Eurasian D cluster | not reported | Single missense mutation | 721A>C (T241P) | ||
| RHD(V147M,A399T) | Eurasian D cluster | not reported | Multiple missense mutations | 1195G>A (A399T) 1195G>A (V147M) | 2016 | ||
| RHD(V174M,G307R) | Eurasian D cluster | not reported | Multiple missense mutations | 520G>A (V174M) 919G>A (G307R) | 2017 | ||
| RHD(V174M,V306I) | Eurasian D cluster | cDe | Multiple missense mutations | 520G>A (V174M) 916G>A (V306I) | 2012 | ||
| RHD(V245L,G263R,K267M) | Eurasian D cluster | not reported | Multiple missense mutations | 733G>C (V245L) 744C>T 787G>A (G263R) 800A>T (K267M) | 2017 | ||
| RHD(V247L) | Eurasian D cluster | not reported | Single missense mutation | 739G>C (V247L) | 2017 | ||
| RHD(V281L) | Eurasian D cluster | not reported | Single missense mutation | 841G>C (V281L) | 2016 | ||
| RHD(V306I,Y311C) | Eurasian D cluster | not reported | hybrid allele | 916G>A (V306I) 932A>G (Y311C) | 2016 | ||
| RHD(V319G) | Eurasian D cluster | not reported | Single missense mutation | 956T>G (V319G) | 2017 | ||
| RHD(V352I) | Eurasian D cluster | not reported | Single missense mutation | 1054G>A (V352I) | 2012 | 2012 | |
| RHD(V50D) | Eurasian D cluster | not reported | Single missense mutation | 149T>A (V50D) | 2016 | ||
| RHD(W393X) | RHD*01N.76 RHD*1179A | Eurasian D cluster | not reported | Nonsense mutation | 1179G>A (W393X) | 2014 | 2014 |
| RHD(X418S) | Eurasian D cluster | not reported | Loss of stop codon | 1253A>C (X418S) | 2014 | ||
| RHD(Y243X) | Eurasian D cluster | not reported | Nonsense mutation | 729T>A (Y243X) | 2017 | ||
| RHD(Y311C) | Eurasian D cluster | not reported | Single missense mutation | 932A>G (Y311C) | 2014 | 2014 | |
| RHD*5'UTR-115C | Eurasian D cluster | not reported | untranslated region | IVS0-115A>C | 2017 | ||
| RHD-cE(5-6)-D | Eurasian D cluster | not reported | hybrid allele | Hybrid RHcE[226P](5-6) | 2015 | ||
| RHD-ceAG.05(2)-D | Eurasian D cluster | not reported | hybrid allele | 254C>G (A85G) 744C>T Hybrid RHCE(2) | 2017 | ||
| RHD-RHCE(2)-RHD(F355S) | Eurasian D cluster | not reported | Complex changes | 1063G>A (G355S) Hybrid RHCE(2) | 2012 | 2012 | |
| RHD-RHCE(5:733-5:787)-RHD | Eurasian D cluster | not reported | Single missense mutation | Hybrid RHCE(5:733-5:787) | 2016 | ||
| RHD-RHcE[226P](5:676-5:733)-RHD | Eurasian D cluster | not reported | hybrid allele | Hybrud RHcE[226P]/5;676-5:733 | 2016 | ||
| RHD-RHCE[245V](5)-RHD | Eurasian D cluster | not reported | hybrid allele | Hybrid RHCE[245V](5) | 2017 | ||
| RHDpsi-OT1 | weak D type 4 cluster | cDe | Complex changes | 609G>A 654G>C (M218I) 667T>G (F223V) 674C>T (S225F) 835G>A (V279M) IVS3-19 dupl 37 IVS7-214ins ACAG | 2012 | ||
| weak D type 145 | RHD* 01W.145 RHD*weak D type 145 | Eurasian D cluster | not reported | Single missense mutation | 41C>G (P14R) |