weak RHD(IVS6-14delTAA)

Structure

RHD(IVS6-14delTAA)

Key changes from standard allele

IVS6-14delTAA

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.940-14 delTAA

Amino acid changes relative to standard protein

ISBT group

Phenotype characterization and grouping

weakened D expression

Phenotypes observed

CcDe (major)

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2008 EU093081 (submitted 2007-08-02, released 2008-09-01)

First full publication: 2013 Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Serology

weak D expression Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Observations

China (general): Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Additional comments

In the intial publication, the allele was dubbed weak D type 81. This nomenclature was not supported by ISBT.

Last update: 2018-05-23 (yyyy-MM-dd)