weak RHD(IVS3+3G>C)

Structure

RHD(IVS3+3G>C)

Key changes from standard allele

IVS3+3G>C

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.486+3 G>C

Amino acid changes relative to standard protein

ISBT group

Phenotype characterization and grouping

weakened D expression

Phenotypes observed

cDEe (major)

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2008 EF407565 (submitted 2007-01-29, released 2008-02-01)

First full publication: 2013 Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Serology

weak D phenotype Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Observations

China (general): EF407565

Additional comments

In the initial publication, the allele is dubbed weak D type 80. This nomenclature was never approved by ISBT.

Last update: 2018-05-23 (yyyy-MM-dd)