weak RHD(960G>A)

Structure

RHD(960G>A)

Key changes from standard allele

960G>A

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.960 G>A

Amino acid changes relative to standard protein

Leu to Leu at codon 320

L320L

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2007 DQ874619 (submitted 2006-08-01, released 2007-09-01)

First full publication: 2015 Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Other relevant descriptions:
alternative splicing LC053447 (submitted 2015-04-28, released 2015-06-04)
LC053444 (submitted 2015-04-28, released 2015-06-04)

ISBT group

Phenotype characterization and grouping

weakened D expression

Serology

weakened D expression: direct agglutination 2+; IAT 4+ Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.

Observations

Japan (general): 13 of 45 samples with weakened D expression Ogasawara K et. al. Vox Sang. 2015 Sep 4. doi: 10.1111/vox.12322.
China (general): DQ874619

Additional comments

Last update: 2015-10-18 (yyyy-MM-dd)