weak D type 9

Structure

RHD(A294P)

Key changes from standard allele

880G>C (A294P)

ISBT allele designation

RHD*01W.9
RHD*weak D type 9

Nucleotide changes relative to "standard RHD"

880 G>C

Amino acid changes relative to standard protein

Ala to Pro at codon 294

A294P

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1999 Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Rhesus Index 0.43 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Observations

Poland (general): population frequency 1:31,200 Orzinska A et. al. Transfusion. 2013 Nov;53(11 Suppl 2):2945-53. doi: 10.1111
South-Western Germany: Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93. Frequency 1:47.619

Additional comments

Last update: 2016-08-28 (yyyy-MM-dd)