weak D type 8

Structure

RHD(G307R)

Key changes from standard allele

919G>A (G307R)

ISBT allele designation

RHD*01W.8
RHD*weak D type 8

Nucleotide changes relative to "standard RHD"

919 G>A

Amino acid changes relative to standard protein

Gly to Arg at codon 307

G307R

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1999 Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Rhesus Index 0.75 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.
weak D expression; Direct agglutination 3+; IAT 4+ Colin Y et. al. Blood. 1991 Nov 15;78(10):2747-52.

Observations

Japan (general): 1 of 45 samples with weak D expression Colin Y et. al. Blood. 1991 Nov 15;78(10):2747-52.
South-Western Germany: Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

Additional comments

Last update: 2015-10-18 (yyyy-MM-dd)