weak D type 6

Structure

RHD(R10Q)

Key changes from standard allele

29G>A (R10Q)

ISBT allele designation

RHD*01W.6
RHD*weak D type 6

Nucleotide changes relative to "standard RHD"

29 G>A

Amino acid changes relative to standard protein

Arg to Gln at codon 10

R10Q

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1999 Wagner FF et. al. Blood. 1999 Jan 1;93(1):385-93.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Rhesus Index 0.79 Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.

Observations

South-Western Germany: Wagner FF et. al. Blood. 2000 Apr 15;95(8):2699-708.
Taiwan: 1 of 7 weak D samples Lin IL et. al. Ann Hematol. 2003 Oct;82(10):617-20.

Additional comments

Last update: 2012-03-25 (yyyy-MM-dd)