weak D type 59

Structure

RHD(L383P)

Key changes from standard allele

1148T>C (L383P)

ISBT allele designation

RHD*01W.59
RHD*weak D type 59

Nucleotide changes relative to "standard RHD"

1148 T>C

Amino acid changes relative to standard protein

Leu to Pro at codon 383

L383P

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2007 EF105446 (submitted 2006-11-03, released 2007-12-01)

First full publication: 2007 Le Marechal C et. al. Transfusion. 2007 May;47(5):858-63.

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

No data

Observations

France (general): Le Marechal C et. al. Transfusion. 2007 May;47(5):858-63.
Germany (general): Doescher A & Wagner FF published on RhesusBase NOTE_2

Additional comments

Last update: 2012-06-17 (yyyy-MM-dd)