weak D type 54

Structure

RHD(S122L)

Key changes from standard allele

365C>T (S122L)

ISBT allele designation

RHD*01W.54
RHD*weak D type 54

Nucleotide changes relative to "standard RHD"

365 C>T

Amino acid changes relative to standard protein

Ser to Leu at codon 122

S122L

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2006 AM396583 (submitted 2006-08-24, released 2006-09-24)

Other relevant descriptions:
DQ869864 (submitted 2007-08-02, released 2007-08-03)

ISBT group

weak D

Phenotype characterization and grouping

weak D type; weakened D expression

Serology

Negative for JAL and JAHK Schmid P et. al. Transfusion. 2010 Jan;50(1):267-9.

Observations

China (general): DQ869864
Turkish descent: AM396583

Additional comments

Last update: 2014-08-03 (yyyy-MM-dd)